NDLI: Efficacy of fipronil combined with permethrin commercial spot on (Effitix®) preventing Culex pipiens from feeding on dogs

Content Provider	Springer Nature Link
Author	Franc, Michel Lienard, Emmanuel Jacquiet, Philippe Bonneau, Stephane Bouhsira, Emilie
Copyright Year	2015
Abstract	A controlled clinical trial was carried out to assess the adulticidal and anti-feeding effectiveness of a spot-on combining fipronil and permethrin (Effitix®, Virbac, Carros, France) in preventing Culex pipiens from feeding on dogs. Twelve dogs with equal sensitivity to mosquitoes were included in the study and divided into two groups of six dogs: an untreated control group and a group treated with Effitix®. All dogs were challenged with 80 females C. pipiens for 90 ± 5 min on days −7, 1, 7, 14, 21, and 28 (day 0 being treatment day). The number of engorged, dead, and live mosquitoes was determined after each exposure to treated and untreated dogs. Dead mosquitoes were also counted 24 h after exposure. The anti-feeding effect of the spot-on formulation was 100, 99.5, 97.7, 98.3, and 96.7 % on days 1, 7, 14, 21, and 28, respectively. The mortality effect was 66.6, 55.9, 38, 17.2, and 12.3 % on days 1, 7, 14, 21, and 28, respectively. At each challenge point, the mortality and anti-feeding effects on mosquitoes were significantly different between the control and treated group (p < 0.05). The results indicate that a combination of permethrin and fipronil could be used as an effective mosquito control strategy in dogs and is therefore recommended for use in a dirofilariasis prevention program.
Starting Page	2093
Ending Page	2097
Page Count	5
File Format	PDF
ISSN	09320113
Journal	Parasitology Research
Volume Number	114
Issue Number	6
e-ISSN	14321955
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2015-03-05
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Culex pipiens Permethrin Fipronil Antifeeding-effect Dogs Effitix® Medical Microbiology Microbiology Immunology
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Veterinary Parasitology Insect Science

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