NDLI: The development of migrating muscle precursor cells

Content Provider	Springer Nature Link
Author	Vasyutina, Elena Birchmeier, Carmen
Copyright Year	2006
Abstract	A major subclass of hypaxial muscle groups is derived from long-range migrating precursor cells that delaminate from the dermomyotome. Migrating precursors are generated on particular axial levels only, i.e. occipitally, cervically, and on the levels of the fore and hind limbs. They express the homeobox gene Lbx1, which provides a useful marker for their visualization. In the mouse, migrating precursor cells give rise to muscles of the extremities, the hypoglossal chord, and the diaphragm. We discuss here the development of this migrating lineage, which critically depends on the correct specification of the precursors in the dermomyotome, their delamination and correct migration. Finally, proliferation at the targets is essential to ensure a correct size of the precursor pool and of the muscle that derives thereof.
Starting Page	37
Ending Page	41
Page Count	5
File Format	PDF
ISSN	03402061
Journal	Anatomy and Embryology
Volume Number	211
Issue Number	1
e-ISSN	14320568
Language	English
Publisher	Springer-Verlag
Publisher Date	2006-09-15
Publisher Place	Berlin/Heidelberg
Access Restriction	Subscribed
Subject Keyword	Neurology Cell Biology Neurosciences
Content Type	Text
Resource Type	Article
Subject	Anatomy Cell Biology Developmental Biology Embryology

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The development of migrating muscle precursor cells