NDLI: Application of bioreactance for cardiac output assessment during exercise in healthy individuals

Content Provider	Springer Nature Link
Author	Elliott, Adrian Hull, James H. Nunan, David Jakovljevic, Djordje G. Brodie, David Ansley, Lesley
Copyright Year	2010
Abstract	In patients with cardiac failure, bioreactance-based cardiac output (CO) monitoring provides a valid non-invasive method for assessing cardiac performance during exercise. The purpose of this study was to evaluate the efficacy of this technique during strenuous exercise in healthy, trained individuals. Fourteen recreational cyclists, mean (SD) age of 34 (8) years and relative peak oxygen uptake of (VO2) 56 (6) ml kg−1 min−1, underwent incremental maximal exercise testing, whilst CO was recorded continuously using a novel bioreactance-based device (CObio). The CObio was evaluated against relationship with VO2, theoretical calculation of arterial-venous oxygen difference (C(a − v) O2) and level of agreement with an inert gas rebreathing method (COrb) using a Bland–Altman plot. Bioreactance-based CO measurement was practical and straightforward in application, although there was intermittent loss of electrocardiograph signal at high-intensity exercise. At rest and during exercise, CObio was strongly correlated with VO2 (r = 0.84; P < 0.001), however, there was evidence of systematic bias with CObio providing lower values than COrb; mean bias (limits of agreement) −19% (14.6 to −53%). Likewise, calculated (C(a − v) O2) was greater when determined using CObio than COrb (P < 0.001), although both devices provided values in excess of those reported in invasive studies. Bioreactance-based determination of CO provides a pragmatic approach to the continuous assessment of cardiac performance during strenuous exercise in trained individuals. Our findings, however, suggest that further work is needed to refine the key measurement determinants of CO using this device to improve measurement accuracy in this setting.
Starting Page	945
Ending Page	951
Page Count	7
File Format	PDF
ISSN	14396319
Journal	European Journal of Applied Physiology
Volume Number	109
Issue Number	5
e-ISSN	14396327
Language	English
Publisher	Springer-Verlag
Publisher Date	2010-03-25
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Rebreathing methods Exercise testing Oxygen uptake Exercise hemodynamics Sports Medicine Occupational Medicine/Industrial Medicine Human Physiology
Content Type	Text
Resource Type	Article
Subject	Orthopedics and Sports Medicine Physiology (medical) Public Health, Environmental and Occupational Health Sports Science

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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