NDLI: Arterial pulse wave velocity and risk factors for peripheral vascular disease

Content Provider	Springer Nature Link
Author	Kanda, T. Nakamura, E. Moritani, T. Yamori, Y.
Copyright Year	2000
Abstract	Non-invasive measurement of arterial pulse wave velocity (PWV) is used to diagnose peripheral vascular disease. We examined the relationship between PWV and risk factors related to peripheral vascular disease [body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), serum total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), atherogenic index (AI) and blood glucose (GLU)] in 45 healthy male volunteers, aged 25–85 years. The correlation coefficient of PWV with age was r=0.46, and the correlation coefficients of PWV with DBP, AI and GLU were r=0.71, 0.56, and 0.22, respectively (P < 0.05). Multiple linear regression analysis revealed that 67% of the variance in PWV could be accounted for by these three variables. The relative contributions of DBP, AI and GLU to PWV were 66%, 26% and 8%, respectively. To test the applicability of PWV for clinical use, a multiple regression equation of PWV derived from these three variables was then applied to male patients with hypertension (n=53), hyperlipidaemia (n=35) or hyperglycaemia (n=39). The results suggest that the multiple regression equation of PWV is an indicator that discriminates between these patient categories and healthy men.
Starting Page	1
Ending Page	7
Page Count	7
File Format	PDF
ISSN	14396319
Journal	European Journal of Applied Physiology
Volume Number	82
Issue Number	1
e-ISSN	14396327
Language	English
Publisher	Springer-Verlag
Publisher Date	2000-05-15
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Content Type	Text
Resource Type	Article
Subject	Orthopedics and Sports Medicine Physiology (medical) Public Health, Environmental and Occupational Health Sports Science

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