NDLI: Tissue oxygenation measured with near-infrared spectroscopy during normobaric and hyperbaric oxygen breathing in healthy subjects

Content Provider	Springer Nature Link
Author	Larsson, Agneta Uusijärvi, Johan Eksborg, Staffan Lindholm, Peter
Copyright Year	2010
Abstract	To evaluate the possibility of using near-infrared spectroscopy (NIRS) to measure tissue oxygenation (StO2) during hyperbaric oxygen (HBO) therapy. Nine healthy volunteers (1 female) age 25−37 years, breathed air or oxygen. Tissue oxygenation was measured using NIRS on the thumb. Subjects were blinded to breathing gas. A range of partial pressures of oxygen were administered in 10-min intervals: 21, 101, 21 kPa (compression to 280 kPa), 59, 280, 59 (decompression), 21 kPa. Data were averaged over last 5 min at each pressure. When switching from air to normobaric oxygen (NBO 101 kPa) StO2 increased from 83% (82−85%, median and interquartile range) to 85% (84−87%) (P < 0.01), while when switching from air at pressure (59 kPa O2) to HBO (280 kPa), StO2 increased from 85% (85−86%) to 88% (87−89%) (P < 0.001). There was no difference between baseline StO2 while air breathing before NBO or after decompression. Values did not reach the maximal value of 100% at any point. The changes in hemoglobin oxygen saturation in tissue registered by the NIRS monitor when switching from air to oxygen followed inspired PO2 under normobaric and hyperbaric conditions.
Starting Page	757
Ending Page	761
Page Count	5
File Format	PDF
ISSN	14396319
Journal	European Journal of Applied Physiology
Volume Number	109
Issue Number	4
e-ISSN	14396327
Language	English
Publisher	Springer-Verlag
Publisher Date	2010-03-10
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Near-infrared spectroscopy (NIRS) Hyperbaric oxygen (HBO) Normobaric oxygen (NBO) Tissue oxygenation (StO2) Sports Medicine Occupational Medicine/Industrial Medicine Human Physiology
Content Type	Text
Resource Type	Article
Subject	Orthopedics and Sports Medicine Physiology (medical) Public Health, Environmental and Occupational Health Sports Science

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