NDLI: Effect of two durations of short-term intermittent hypoxia on ventilatory chemosensitivity in humans

Content Provider	Springer Nature Link
Author	Katayama, Keisho Ishida, Koji Iwasaki, Ken ichi Miyamura, Miharu
Copyright Year	2008
Abstract	The purpose of this study was to clarify the influence of duration of intermittent hypoxia per day on ventilatory chemosensitivity. Subjects were assigned to three different groups according to the duration of exposure to intermittent hypoxia (12.3 ± 0.2% O2): a first group (H-1, n = 6) was exposed to hypoxia for 1 h per day, the second group (H-2, n = 6) was exposed for 3 h per day, and the third (C, n = 7) was used as control. Hypoxic and hypercapnic ventilatory responses (HVR and HCVR) were determined before and after 1 week of intermittent hypoxia. HVR was increased significantly (P < 0.05) after intermittent hypoxia in both the H-1 and H-2 groups. However, there was no significant difference in magnitude of increased HVR between H-1 and H-2 groups. HCVR did not show any changes in all groups after intermittent hypoxia. These results suggest that 1 h of daily exposure is as equally effective as 3 h of daily exposure to severe hypoxia for a short period for enhancing ventilatory chemosensitivity to hypoxia.
Starting Page	815
Ending Page	821
Page Count	7
File Format	PDF
ISSN	14396319
Journal	European Journal of Applied Physiology
Volume Number	105
Issue Number	5
e-ISSN	14396327
Language	English
Publisher	Springer-Verlag
Publisher Date	2009-01-06
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Hypoxic ventilatory chemosensitivity Hypercapnic ventilatory chemosensitivity Intermittent exposure to hypoxia Sports Medicine Occupational Medicine/Industrial Medicine Human Physiology
Content Type	Text
Resource Type	Article
Subject	Orthopedics and Sports Medicine Physiology (medical) Public Health, Environmental and Occupational Health Sports Science

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