NDLI: Skeletal muscle size is a major predictor of intramuscular fat content regardless of age

Content Provider	Springer Nature Link
Author	Akima, Hiroshi Yoshiko, Akito Hioki, Maya Kanehira, Nana Shimaoka, Kiyoshi Koike, Teruhiko Sakakibara, Hisataka Oshida, Yoshiharu
Copyright Year	2015
Abstract	Skeletal muscles of older individuals have a larger amount of intramuscular adipose tissue (IntraMAT) than those of younger individuals. It is not understood how aging affects the IntraMAT content of individual muscles of the thigh. We assessed the relationship between IntraMAT content and skeletal muscle cross-sectional area (CSA), subcutaneous adipose tissue CSA, biochemical blood profiles, and physical activity.Fifteen older (70.7 ± 3.8 years) and 15 younger (20.9 ± 0.3 years) men and women participated in this study. Magnetic resonance imaging of the right thigh was taken to measure IntraMAT content and skeletal muscle CSA for the quadriceps femoris (QF), hamstrings (HM), adductor (AD) muscle groups and subcutaneous adipose tissue CSA of the thigh. Fasting blood samples were collected to measure plasma lipids, adiponectin, and HbA1c levels.IntraMAT content in QF, HM, and AD for the Older group was significantly higher than in the Younger group. However, skeletal muscle CSA normalized by body weight (skeletal muscle CSA/bw) in the QF (P < 0.001) and total thigh (P < 0.01) were significantly lower in the Older group compared with the Younger group.There were no significant differences in HM and AD. Stepwise regression analysis with IntraMAT content as a dependent variable revealed that skeletal muscle CSA/bw of the thigh was the only predictive variable for IntraMAT content in Older and Younger groups.These results suggest that skeletal muscle size could be a major determinant of IntraMAT content regardless of age.
Starting Page	1627
Ending Page	1635
Page Count	9
File Format	PDF
ISSN	14396319
Journal	European Journal of Applied Physiology
Volume Number	115
Issue Number	8
e-ISSN	14396327
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2015-03-11
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Skeletal muscle Sarcopenia Magnetic resonance imaging Blood lipids Human Physiology Occupational Medicine/Industrial Medicine Sports Medicine
Content Type	Text
Resource Type	Article
Subject	Orthopedics and Sports Medicine Physiology (medical) Public Health, Environmental and Occupational Health Sports Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Ultrasonographic assessment of human skeletal muscle size

Evaluation of exercised or cooled skeletal muscle on the basis of diffusion-weighted magnetic resonance imaging

Prediction and validation of total and regional skeletal muscle mass by ultrasound in Japanese adults

The unfolded protein response in human skeletal muscle is not involved in the onset of glucose tolerance impairment induced by a fat-rich diet

Supplemental oxygen and muscle metabolism in mitochondrial myopathy patients

Effect of multiple set on intramuscular metabolic stress during low-intensity resistance exercise with blood flow restriction

Exercise improves skeletal muscle insulin resistance without reduced basal mTOR/S6K1 signaling in rats fed a high-fat diet

Comparison between magnetic resonance imaging and electrical impedance myography for evaluating lumbar skeletal muscle composition

Skeletal muscle glycogen content and particle size of distinct subcellular localizations in the recovery period after a high-level soccer match

Skeletal muscle size is a major predictor of intramuscular fat content regardless of age

Similar Documents

Ultrasonographic assessment of human skeletal muscle size

Evaluation of exercised or cooled skeletal muscle on the basis of diffusion-weighted magnetic resonance imaging

Prediction and validation of total and regional skeletal muscle mass by ultrasound in Japanese adults

The unfolded protein response in human skeletal muscle is not involved in the onset of glucose tolerance impairment induced by a fat-rich diet

Supplemental oxygen and muscle metabolism in mitochondrial myopathy patients

Effect of multiple set on intramuscular metabolic stress during low-intensity resistance exercise with blood flow restriction

Exercise improves skeletal muscle insulin resistance without reduced basal mTOR/S6K1 signaling in rats fed a high-fat diet

Comparison between magnetic resonance imaging and electrical impedance myography for evaluating lumbar skeletal muscle composition

Skeletal muscle glycogen content and particle size of distinct subcellular localizations in the recovery period after a high-level soccer match

Skeletal muscle size is a major predictor of intramuscular fat content regardless of age