NDLI: Cardiovascular responses to upright and supine exercise in humans after 6 weeks of head-down tilt (−6°)

Content Provider	Springer Nature Link
Author	Sundblad, P. Spaak, J. Linnarsson, D.
Copyright Year	2000
Abstract	Seven healthy men performed steady-state dynamic leg exercise at 50 W in supine and upright postures, before (control) and repeatedly after 42 days of strict head-down tilt (HDT) (−6°) bedrest. Steady-state heart rate (f c), mean arterial blood pressure, cardiac output (Q˙ c), and stroke volume (SV) were recorded. The following data changed significantly from control values. The f c was elevated in both postures at least until 12 days, but not at 32 days after bedrest. Immediately after HDT, SV and Q˙ c were decreased by 25 (SEM 3)% and 19 (SEM 3)% in supine, and by 33 (SEM 5)% and 20 (SEM 3)% in upright postures, respectively. Within 2 days there was a partial recovery of SV in the upright but not in the supine posture. The SV and Q˙ c during supine exercise remained significantly decreased for at least a month. Submaximal oxygen uptake did not change after HDT. We concluded that the cardiovascular response to exercise after prolonged bedrest was impaired for so long that it suggested that structural cardiac changes had developed during the HDT period.
Starting Page	303
Ending Page	309
Page Count	7
File Format	PDF
ISSN	14396319
Journal	European Journal of Applied Physiology
Volume Number	83
Issue Number	4
e-ISSN	14396327
Language	English
Publisher	Springer-Verlag
Publisher Date	2000-11-14
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Content Type	Text
Resource Type	Article
Subject	Orthopedics and Sports Medicine Physiology (medical) Public Health, Environmental and Occupational Health Sports Science

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