NDLI: Nanoparticle dermal absorption and toxicity: a review of the literature

Content Provider	Springer Nature Link
Author	Crosera, Matteo Bovenzi, Massimo Maina, Giovanni Adami, Gianpiero Zanette, Caterina Florio, Chiara Filon Larese, Francesca
Copyright Year	2009
Abstract	Nanotechnologies are among the fastest growing areas of scientific research and have important applications in a wide variety of fields. The data suggest that in the future workers and consumers exposed to nanoparticles will significantly increase.At now there are gaps in understanding about the human and environmental risk that manufactured nanoparticles pose for occupational exposed people and for consumers. There is a need for assessing the health and environmental impacts, the nanoparticles life cycle, the human exposure routes, the behavior of nanoparticles in the body, and the risk for workers. Possible routes of entry into the body include inhalation, absorption through the skin or digestive tract, injection, and absorption or implantation for drugs delivery systems. In particular, dermal absorption and skin penetration of nanoparticles needs a better evaluation because few and contradictory data are present in the literature, mainly on titanium dioxide.There are limited data on carbon-based nanoparticles and very few data on other metal nanoparticles increasingly used in industry. The article reviews the literature on the percutaneous absorption of nanoparticles and their effect on skin.
Starting Page	1043
Ending Page	1055
Page Count	13
File Format	PDF
ISSN	03400131
Journal	International Archives of Occupational and Environmental Health
Volume Number	82
Issue Number	9
e-ISSN	14321246
Language	English
Publisher	Springer-Verlag
Publisher Date	2009-08-25
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Skin absorption Nanoparticles Review Environmental Health Rehabilitation Occupational Medicine/Industrial Medicine
Content Type	Text
Resource Type	Article
Subject	Public Health, Environmental and Occupational Health

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