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| Content Provider | Springer Nature Link |
|---|---|
| Author | Lee, Kyoung Ho Vermeulen, Roel Lenters, Virissa Cho, Soo Hun Strickland, Paul T. Kang, Daehee |
| Copyright Year | 2008 |
| Abstract | This study was conducted to investigate the dominant sources of the urinary pyrene metabolite, 1-hydroxypyrene glucuronide (1-OHPG), in South Korean children.Urine samples were collected from 102 non-smoking children (aged 10–14). Urinary 1-OHPG was assayed by synchronous fluorescence spectroscopy, following immuno-affinity purification using monoclonal antibody 8E11. Urinary cotinine, a metabolite of nicotine, was measured by GC/MS. Information on environmental tobacco smoke (ETS) exposure, diet, fuel type for heating home, and other possible sources of PAH exposure was collected by self-administered questionnaires.Mean (±SE) 1-OHPG levels were 1.64 (±0.06) ng/ml (range 0.04–3.27 ng/ml). Two multiple linear regression analyses (differing in how ETS was approximated: by parental smoking or urinary cotinine) revealed a positive association between urinary 1-OHPG levels and parental smoking at home (P = 0.007), log urinary cotinine (P = 0.165), frequent grilled (shell)fish consumption (P = 0.061), and living in a commercial/other zone (P = 0.007) versus a residential or industrial zone. No consistent associations were found between 1-OHPG and the child’s sex, grilled meat consumption, or fuels used to heat the home.These results support that ETS, frequent grilled fish consumption, and the ambient environment are important predictors of urinary 1-OHPG levels in South Korean children. |
| Starting Page | 961 |
| Ending Page | 968 |
| Page Count | 8 |
| File Format | |
| ISSN | 03400131 |
| Journal | International Archives of Occupational and Environmental Health |
| Volume Number | 82 |
| Issue Number | 8 |
| e-ISSN | 14321246 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2008-11-20 |
| Publisher Place | Berlin, Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | 1-Hydroxypyrene glucuronide Polycyclic aromatic hydrocarbons Cotinine Environmental tobacco smoke Diet Children Environmental Health Rehabilitation Occupational Medicine/Industrial Medicine |
| Content Type | Text |
| Resource Type | Article |
| Subject | Public Health, Environmental and Occupational Health |
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