NDLI: Immunohistochemical localization of sodium-dependent l-ascorbic acid transporter 1 protein in rat kidney

Content Provider	Springer Nature Link
Author	Lee, Ju Hyun Oh, Chang Seok Mun, Ga Hee Kim, Jae hyup Chung, Yoon Hee Hwang, Young Il Shin, Dong Hoon Lee, Wang Jae
Copyright Year	2006
Abstract	Recently, two l-ascorbic acid transporters were identified; sodium-dependent vitamin C transporter (SVCT) 1 and SVCT2. The previous study suggested that SVCT protein might be present on the apical membrane in the straight segment (S3) of proximal tubule. In the present study, SVCT1 immunoreactivity (IR) was observed in the brush border of proximal straight tubules in the medullary ray of renal cortex and the outer stripe of outer medulla, while SVCT2 IR was not localized in any region of the kidney. Since the mechanism of VC reabsorption in the kidney has not been fully elucidated up to the present time, it is meaningful to demonstrate the exact cellular distribution of SVCT protein in the kidney.
Starting Page	491
Ending Page	494
Page Count	4
File Format	PDF
ISSN	09486143
Journal	Histochemistry and Cell Biology
Volume Number	126
Issue Number	4
e-ISSN	1432119X
Language	English
Publisher	Springer-Verlag
Publisher Date	2006-05-04
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	l-ascorbic acid Sodium-dependent vitamin C transporter Kidney Proximal tubule Immunohistochemistry
Content Type	Text
Resource Type	Article
Subject	Cell Biology Histology Molecular Biology Medical Laboratory Technology

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Immunohistochemical localization of sodium-dependent l-ascorbic acid transporter 1 protein in rat kidney