NDLI: Fractal analysis of viscoelastic data with automated gel point location and its potential application in the investigation of therapeutically modified blood coagulation

Content Provider	Springer Nature Link
Author	Evans, P. Adrian Lawrence, Matthew Morris, R. H. Keith Thirumalai, Naresh Munro, Roger Wakeman, Lisa Beddel, Andrew Williams, P. Rhodri Barrow, Matthew Curtis, Daniel Brown, M. Rowan Hawkins, Karl
Copyright Year	2010
Abstract	This study reports an automated numerical method for the location of the gel point in oscillatory shear data and demonstrates its potential application in measurements on therapeutically modified (heparinised) samples of healthy coagulating blood. Heparin prolongs the onset of clot formation and has a significant effect on the microstructure of the clot which is eventually formed. The results demonstrate the potential of this rheometrical technique as a new tool for monitoring the effect of heparin on samples of whole blood with significantly better linearity of response within the therapeutic range than another global coagulation monitoring technique (thromboelastography) which has previously been used.
Starting Page	901
Ending Page	908
Page Count	8
File Format	PDF
ISSN	00354511
Journal	Rheologica Acta
Volume Number	49
Issue Number	9
e-ISSN	14351528
Language	English
Publisher	Springer-Verlag
Publisher Date	2010-07-25
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Incipient clot Anti-coagulant Fractal dimension Rheometry Food Science Polymer Sciences Characterization and Evaluation of Materials Mechanical Engineering Soft and Granular Matter, Complex Fluids and Microfluidics
Content Type	Text
Resource Type	Article
Subject	Mechanics of Materials Condensed Matter Physics Materials Science

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