Please wait, while we are loading the content...
Please wait, while we are loading the content...
| Content Provider | Springer Nature Link |
|---|---|
| Author | Santander Ortega, Manuel J. Loza López, María V. Bastos González, Delfina Peula García, José M. Ortega Vinuesa, Juan L. |
| Copyright Year | 2009 |
| Abstract | In the last few years, a great attention has been paid to core-shell structured lipid nanocapsules. The interest of these colloids lies in their very promising applications as delivery systems of hydrophobic drugs or as DNA carriers. The aim of this work was to provide fuller knowledge concerning the physicochemical properties of these new colloidal particles, paying special attention to the role played by the constituting components. Our lipid nanocapsules were comprised of a triglyceride-lecithin core surrounded by a chitosan and/or poloxamer (Pluronic® F68) shell. Four different systems were formulated by varying the chitosan and poloxamer contents. We have estimated their shell composition from electrokinetic mobility measurements and stability studies. They revealed a high incorporation of chitosan to the shell, while Pluronic® F68 only presented a secondary role during the nanocapsule formation, providing final systems with low poloxamer content. In addition, the stability studies, performed not only on ideal solutions but also on simulated physiological fluids, revealed that hydration forces were crucial to maintain the integrity of these nanocapsules under physicochemical conditions similar to those found in real physiological fluids. Theoretical treatment of stability data has allowed us to determine the role that ions play on hydration forces when they act as counterions. |
| Starting Page | 159 |
| Ending Page | 172 |
| Page Count | 14 |
| File Format | |
| ISSN | 0303402X |
| Journal | Colloid and Polymer Science |
| Volume Number | 288 |
| Issue Number | 2 |
| e-ISSN | 14351536 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2009-10-27 |
| Publisher Place | Berlin/Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Lipid nanocapsules Poloxamer Chitosan Hydration forces Colloidal stability Food Science Physical Chemistry Characterization and Evaluation of Materials Soft and Granular Matter, Complex Fluids and Microfluidics Polymer Sciences |
| Content Type | Text |
| Resource Type | Article |
| Subject | Colloid and Surface Chemistry Materials Chemistry Physical and Theoretical Chemistry Polymers and Plastics |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|