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| Content Provider | Springer Nature Link |
|---|---|
| Author | Lubinus, Tim Barnsteiner, Andreas Skurk, Thomas Hauner, Hans Engel, Karl Heinz |
| Copyright Year | 2012 |
| Abstract | The objective was to investigate the metabolic fate of phytosteryl/-stanyl fatty acid and ferulic acid esters upon consumption by healthy humans.A capillary gas chromatographic methodology was employed to follow a randomized, single-blind three group crossover clinical trial and to quantify simultaneously individual intact esters, liberated phytosterols/-stanols and their metabolites in feces. Skimmed milk drinking yogurts enriched with complex mixtures of phytosteryl/-stanyl fatty acid esters and ferulates, respectively, were employed as food carriers.On average, 73 % of total plant stanyl fatty acid esters and 80 % of total plant steryl fatty acid esters were hydrolyzed. Among the individuals, the hydrolysis rates ranged from 40 to 96 %. In addition, there were subject-dependent discrepancies between the amounts of phytosterols/-stanols actually determined in the feces and the calculated hydrolysis rates. On average, 69 % of the amounts of sterols/stanols expected from the amounts of remaining intact esters were found.The study revealed large interindividual variability regarding the recoveries of dietary phytosteryl/-stanyl esters upon gastrointestinal passage in healthy humans. Nevertheless, there was a significant impact of the acid moiety (oleate = linoleate = linolenate > eicosanoate > palmitate > ferulate) on the hydrolysis rates; the influence of the phytosterol/-stanol moiety was less pronounced. |
| Starting Page | 997 |
| Ending Page | 1013 |
| Page Count | 17 |
| File Format | |
| ISSN | 14366207 |
| Journal | European Journal of Nutrition |
| Volume Number | 52 |
| Issue Number | 3 |
| e-ISSN | 14366215 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2012-07-10 |
| Publisher Place | Berlin, Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Phytosteryl/-stanyl fatty acid esters γ-Oryzanol Phytosterols Hydrolysis Metabolization Functional food Randomized clinical trial Nutrition |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nutrition and Dietetics Medicine |
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