NDLI: Metabolic and behavioural effects of sucrose and fructose/glucose drinks in the rat

Please wait, while we are loading the content...

Effect of consumption of tomato juice enriched with n-3 polyunsaturated fatty acids on the lipid profile, antioxidant biomarker status, and cardiovascular disease risk in healthy women

Micronutrient status in lactating mothers before and after introduction of fortified flour: cross-sectional surveys in Maela refugee camp

Hypolipidemic and antioxidant effects of hydroxycinnamic acids, quercetin, and cyanidin 3-glucoside in hypercholesterolemic erythrocytes (in vitro study)

Metabolic and behavioural effects of sucrose and fructose/glucose drinks in the rat

Anti-proliferative and pro-apoptotic activities of hydroxytyrosol on different tumour cells: the role of extracellular production of hydrogen peroxide

CYP1A1 is overexpressed upon incubation of breast cancer cells with a polyphenolic cocoa extract

Does a small difference in iodine status among children in two regions of Belgium translate into a different prevalence of thyroid nodular diseases in adults?

Comparative study of hypocholesterolemic and hypolipidemic effects of conjugated linolenic acid isomers against induced biochemical perturbations and aberration in erythrocyte membrane fluidity

Influence of extra virgin olive oil diet enriched with hydroxytyrosol in a chronic DSS colitis model

The sourdough fermentation may enhance the recovery from intestinal inflammation of coeliac patients at the early stage of the gluten-free diet

European Journal of Nutrition : Volume 51, Issue 3, April 2012

European Journal of Nutrition : Volume 51, Issue 2, March 2012

European Journal of Nutrition : Volume 51, Issue 1, Supplement,March 2012

European Journal of Nutrition : Volume 51, Issue 1, February 2012

European Journal of Nutrition : Volume 50

European Journal of Nutrition : Volume 49

European Journal of Nutrition : Volume 48

European Journal of Nutrition : Volume 47

European Journal of Nutrition : Volume 46

European Journal of Nutrition : Volume 45

European Journal of Nutrition : Volume 44

European Journal of Nutrition : Volume 43

European Journal of Nutrition : Volume 42

European Journal of Nutrition : Volume 41

European Journal of Nutrition : Volume 40

European Journal of Nutrition : Volume 39

European Journal of Nutrition : Volume 38

European Journal of Nutrition : Volume 37

European Journal of Nutrition : Volume 36

Metabolic and behavioural effects of sucrose and fructose/glucose drinks in the rat

Content Provider	Springer Nature Link
Author	Sheludiakova, Anastasia Rooney, Kieron Boakes, Robert A.
Copyright Year	2011
Abstract	Overconsumption of sugar-sweetened beverages, in particular carbonated soft drinks, promotes the development of overweight and obesity and is associated with metabolic disturbances, including intrahepatic fat accumulation and metabolic syndrome. One theory proposes that drinks sweetened with high-fructose corn syrup are particularly detrimental to health, as they contain fructose in its ‘free’ monosaccharide form. This experiment tested whether consuming ‘free’ fructose had a greater impact on body weight and metabolic abnormalities than when consumed ‘bound’ within the disaccharide sucrose.Male Hooded Wistar rats were given free access for 56 days to 10% sucrose (Group Suc), 10%, 50/50 fructose/glucose (Group FrucGluc) or water control drinks (Group Control), plus chow. Caloric intake and body weights were measured throughout the protocol, and the following metabolic indices were determined between days 54 and 56: serum triglycerides, liver triglycerides, retroperitoneal fat and oral glucose tolerance.Animals with access to sugar beverages consumed 20% more calories, but did not show greater weight gain than controls. Nevertheless, they developed larger abdominal fat pads, higher triglyceride levels and exhibited impaired insulin/glucose homeostasis. Comparison of the two sugars revealed increased fasting glycaemia in the FrucGluc group, but not in Suc group, whereas the Suc group was more active in an open field.A metabolic profile indicating increased risk of diabetes mellitus and cardiovascular disease was observed in animals given access to sugar-sweetened beverages. Notably, ‘free’ fructose disrupted glucose homeostasis more than did ‘bound’ fructose, thus posing a greater risk of progression to type 2 diabetes.
Starting Page	445
Ending Page	454
Page Count	10
File Format	PDF
ISSN	14366207
Journal	European Journal of Nutrition
Volume Number	51
Issue Number	4
e-ISSN	14366215
Language	English
Publisher	Springer-Verlag
Publisher Date	2011-07-29
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Metabolic syndrome Sucrose Fructose Glucose High-fructose corn syrup Insulin resistance Glucose tolerance Triglycerides Behaviour Nutrition
Content Type	Text
Resource Type	Article
Subject	Nutrition and Dietetics Medicine

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Excessive Intake of High-Fructose Corn Syrup Drinks Induces Impaired Glucose Tolerance

Role of Fructose-Containing Sugars in the Epidemics of Obesity and Metabolic Syndrome

Endocrine and metabolic effects of consuming beverages sweetened with fructose, glucose, sucrose, or high fructose corn syrup

Consumption of Honey, Sucrose, and High-Fructose Corn Syrup Produces Similar Metabolic Effects in Glucose-Tolerant and -Intolerant $Individuals^{1},^{2}$

Controversies about sugars consumption: state of the science

Twenty-four-hour endocrine and metabolic profiles following consumption of high-fructose corn syrup-, sucrose-, fructose-, and glucose-sweetened beverages with meals

No Effect of Added Sugar Consumed at Median American Intake Level on Glucose Tolerance or Insulin Resistance

Re. 'Fructose content in popular beverages made with and without high fructose corn syrup'.

High dietary fructose intake: Sweet or bitter life?

Metabolic and behavioural effects of sucrose and fructose/glucose drinks in the rat

Similar Documents

Excessive Intake of High-Fructose Corn Syrup Drinks Induces Impaired Glucose Tolerance

Role of Fructose-Containing Sugars in the Epidemics of Obesity and Metabolic Syndrome

Endocrine and metabolic effects of consuming beverages sweetened with fructose, glucose, sucrose, or high fructose corn syrup

Consumption of Honey, Sucrose, and High-Fructose Corn Syrup Produces Similar Metabolic Effects in Glucose-Tolerant and -Intolerant $Individuals^{1},^{2}$

Controversies about sugars consumption: state of the science

Twenty-four-hour endocrine and metabolic profiles following consumption of high-fructose corn syrup-, sucrose-, fructose-, and glucose-sweetened beverages with meals

No Effect of Added Sugar Consumed at Median American Intake Level on Glucose Tolerance or Insulin Resistance

Re. 'Fructose content in popular beverages made with and without high fructose corn syrup'.

High dietary fructose intake: Sweet or bitter life?

Metabolic and behavioural effects of sucrose and fructose/glucose drinks in the rat