NDLI: A model of erythropoiesis in adults with sufficient iron availability

Content Provider	Springer Nature Link
Author	Fuertinger, Doris H. Levin, Nathan W. Kotanko, Peter Kappel, Franz Thijssen, Stephan
Copyright Year	2012
Abstract	In this paper we present a model for erythropoiesis under the basic assumption that sufficient iron availability is guaranteed. An extension of the model including a sub-model for the iron dynamics in the body is topic of present research efforts. The model gives excellent results for a number of important situations: recovery of the red blood cell mass after blood donation, adaptation of the number of red blood cells to changes in the altitude of residence and, most important, the reaction of the body to different administration regimens of erythropoiesis stimulating agents, as for instance in the case of pre-surgical administration of Epoetin-α. The simulation results concerning the last item show that choosing an appropriate administration regimen can reduce the total amount of the administered drug considerably. The core of the model consists of structured population equations for the different cell populations which are considered. A key feature of the model is the incorporation of neocytolysis.
Ending Page	1240
Page Count	32
Starting Page	1209
File Format	PDF
ISSN	03036812
e-ISSN	14321416
Journal	Journal of Mathematical Biology
Issue Number	6
Volume Number	66
Language	English
Publisher	Springer-Verlag
Publisher Date	2012-04-18
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Erythropoiesis Population dynamics (general) PDEs in connection with biology and other natural sciences Mathematical and Computational Biology Neocytolysis Physiology (general) Applications of Mathematics Structured population models
Content Type	Text
Resource Type	Article
Subject	Applied Mathematics Agricultural and Biological Sciences Modeling and Simulation

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Analysis of unstable behavior in a mathematical model for erythropoiesis

Is a nonlocal diffusion strategy convenient for biological populations in competition?

Stochastic simulation of structured skin cell population dynamics

Modeling the spread of Phytophthora

Noisy threshold in neuronal models: connections with the noisy leaky integrate-and-fire model

Mathematical modeling of Myosin induced bistability of Lamellipodial fragments

Optimal Screening in Structured SIR Epidemics

A two layers monodomain model of cardiac electrophysiology of the atria

Analysis of the Trojan Y chromosome model for eradication of invasive species in a dendritic riverine system

A model of erythropoiesis in adults with sufficient iron availability

Similar Documents

Analysis of unstable behavior in a mathematical model for erythropoiesis

Is a nonlocal diffusion strategy convenient for biological populations in competition?

Stochastic simulation of structured skin cell population dynamics

Modeling the spread of Phytophthora

Noisy threshold in neuronal models: connections with the noisy leaky integrate-and-fire model

Mathematical modeling of Myosin induced bistability of Lamellipodial fragments

Optimal Screening in Structured SIR Epidemics

A two layers monodomain model of cardiac electrophysiology of the atria

Analysis of the Trojan Y chromosome model for eradication of invasive species in a dendritic riverine system

A model of erythropoiesis in adults with sufficient iron availability