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| Content Provider | Springer Nature Link |
|---|---|
| Author | Vieira, Jessica Manya B. D. Boente, Renata F. Miranda, Karla Rodrigues Avelar, Kátia E. S. Domingues, Regina M. C. P. Ferreira, Maria Candida de S. |
| Copyright Year | 2005 |
| Abstract | In this study, 197 strains of Bacteroides genus from different species and origins were evaluated with regard to their susceptibility to 5-nitroimidazoles (5-Ni)—such as tinidazole, ornidazole, and metronidazole—using the agar dilution method. The presence of nim genes was also investigated by polymerase chain reaction. It was found that 5.6% of Bacteroides strains among all origins showed decreased susceptibility (minimum inhibitory concentrations varying from 4 to 16 μg/ml) to at least one of the imidazoles studied without any known nim gene associate. Also, we detected one strain isolated from a polluted aquatic environment in which one nim gene was found and characterized as nim B using restriction fragment length polymorphism and sequencing. Hence, resistance to 5-Ni should be monitored closely because they constitute, among few drugs, the ones quite effective in treating Bacteroides infections. |
| Starting Page | 27 |
| Ending Page | 32 |
| Page Count | 6 |
| File Format | |
| ISSN | 03438651 |
| Journal | Current Microbiology |
| Volume Number | 52 |
| Issue Number | 1 |
| e-ISSN | 14320991 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2005-12-26 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Biotechnology Microbiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Microbiology Applied Microbiology and Biotechnology |
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