NDLI: Dendritic cells in atherosclerosis

Content Provider	Springer Nature Link
Author	Subramanian, Manikandan Tabas, Ira
Copyright Year	2013
Abstract	Atherosclerosis is a chronic inflammatory disease with activation of both the innate and adaptive arms of the immune system. Dendritic cells (DCs) are potent activators of adaptive immunity and have been identified in the normal arterial wall and within atherosclerotic lesions. Recent evidence points to a functional role for DCs in all stages of atherosclerosis because of their myriad functions including lipid uptake, antigen presentation, efferocytosis, and inflammation resolution. Moreover, DC-based vaccination strategies are currently being developed for the treatment of atherosclerosis. This review will focus on the current evidence as well as the proposed roles for DCs in the pathogenesis of atherosclerosis and discuss future therapeutic strategies.
Starting Page	93
Ending Page	102
Page Count	10
File Format	PDF
ISSN	18632297
Journal	Springer Seminars in Immunopathology
Volume Number	36
Issue Number	1
e-ISSN	18632300
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2013-11-06
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Dendritic cells Atherosclerosis Tregs Efferocytosis Immunology Internal Medicine
Content Type	Text
Resource Type	Article
Subject	Immunology and Allergy Immunology

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Dendritic cells in atherosclerosis