NDLI: Macrophage ion currents are fit by a fractional model and therefore are a time series with memory

Content Provider	Springer Nature Link
Author	Domínguez, Darío Manuel Marín, Mariela Camacho, Marcela
Copyright Year	2009
Abstract	We studied macroscopic ion currents from macrophages and compared their patterns of behavior using classical and fractal analysis. Peak and steady state currents were measured respectively at the beginning and end of a voltage-clamp pulse. Hurst coefficients H and fractional dimensions were calculated for the current fluctuations (I H ) during the intervening interval; these fluctuations are usually assumed to be white noise. We show that I H is different from 0.5 and that the increments are stationary, indicating that the dynamic model has memory and that the intervening current fluctuations cannot be considered as white noise. I H is less than 0.5, implying an antipersistent pattern. In addition, we show that the relation between inactivation and I H versus voltage V fit an equation I H (V) = f(V, α, m, d), where α is associated with fractional calculus and m and d are free parameters. Fitting by a fractional model confirms that the phenomenon has memory.
Starting Page	457
Ending Page	464
Page Count	8
File Format	PDF
ISSN	01757571
Journal	European Biophysics Journal
Volume Number	38
Issue Number	4
e-ISSN	14321017
Language	English
Publisher	Springer-Verlag
Publisher Date	2009-01-09
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Fractal Macrophage Ion current Fractional Memory Nanotechnology Neurobiology Membrane Biology Cell Biology Biophysics/Biomedical Physics Biochemistry
Content Type	Text
Resource Type	Article
Subject	Medicine Biophysics

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Macrophage ion currents are fit by a fractional model and therefore are a time series with memory

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