NDLI: Time Trends in Serum Organochlorine Pesticides and Polychlorinated Biphenyls in the General Population of Biscay, Spain

Content Provider	Springer Nature Link
Author	Zubero, Miren Begoña Aurrekoetxea, Juan J. Murcia, Mario Ibarluzea, Jesus M. Goñi, Fernando Jiménez, Cristina Ballester, Ferran
Copyright Year	2015
Abstract	Despite the measures adopted, levels of organochlorine compounds (OCs) are still being detected in the human body. This study aimed to explore factors related to changes in the concentrations of polychlorinated biphenyls (PCBs) and pesticide OCs in blood samples obtained from a general population cohort. Two cross-sectional samples were taken from 162 adults (2–75 years of age), with a gap of 2 years, from four areas in Biscay (Spain). More than 75 % had quantifiable levels of hexachlorobenzene (HCB), beta-hexachlorocyclohexane (β-HCH), dichlorodiphenyldichloroethylene, and PCBs 138 153 and 180. During this time, significant changes were observed: PCB 180 and HCB levels increased, and PCB 138 and β-HCH levels decreased. Regarding age, this study shows a decrease suggesting a cohort effect. The period was not related to the decrease of levels in all age intervals, but a statistically significant increase of PCBs in older people was found. High body mass index was associated with lower PCB 180 levels and greater HCH levels. Inversely, greater levels of HCB and β-HCH were in those who had lost weight before the study. Levels of HCB and β-HCH were also greater in women who had had children, although they were lower in those who breastfed. Levels of these same OCs were greater in fish consumers, whereas those of PCBs 138 and 153 were greater in those who consumed local produce; all of these trends were close to significance. Efforts should continue to decrease exposure to these pollutants and to assess their influence on general population.
Starting Page	476
Ending Page	488
Page Count	13
File Format	PDF
ISSN	00904341
Journal	Archives of Environmental Contamination and Toxicology
Volume Number	68
Issue Number	3
e-ISSN	14320703
Language	English
Publisher	Springer US
Publisher Date	2015-01-23
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Ecotoxicology Pollution Environmental Health Environmental Chemistry Soil Science & Conservation Environmental Monitoring/Analysis
Content Type	Text
Resource Type	Article
Subject	Pollution Health, Toxicology and Mutagenesis Medicine Toxicology

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