NDLI: Induction and Recovery of Estrogenic Effects After Short-Term 17β-Estradiol Exposure in Juvenile Rainbow Trout (Oncorhynchus mykiss)

Content Provider	Springer Nature Link
Author	Osachoff, H. L. Shelley, L. K. Furtula, V. Aggelen, G. C. Kennedy, C. J.
Copyright Year	2013
Abstract	Estrogenic compounds found in the aquatic environment include natural and synthetic estrogen hormones as well as other less potent estrogenic xenobiotics. In this study, a comprehensive approach was used to examine effects on fish endocrine system endpoints during a short-term xenoestrogen exposure as well as after post-exposure recovery. Rainbow trout (Oncorhynchus mykiss) were exposed to an aqueous 17β-estradiol (E2) concentration of 0.473 μg l−1 for 2 and 7 days (d) followed by a 14-d recovery period. At d2 and d7, plasma E2 concentrations in treated fish were 458- and 205-fold higher than in control fish and 23- and 16-fold higher than the exposure water concentration. E2 treatment resulted in significant increases in hepatosomatic index (HSI), plasma vitellogenin (VTG) protein concentrations, and liver VTG and estrogen receptor alpha mRNA levels. All of these parameters, with the exception of plasma VTG protein, returned to baseline values during the recovery period. Plasma cortisol concentrations were unaffected by treatment. This research shows varied time frames of the estrogen-responsive molecular-, biochemical-, and tissue-level alterations, as well as their persistence, in juvenile rainbow trout treated with aqueous E2. These results have implications for feral rainbow trout exposed to xenoestrogens and indicate the importance of evaluating a comprehensive suite of endpoints in assessing the impact of this type of environmental contaminant.
Starting Page	276
Ending Page	285
Page Count	10
File Format	PDF
ISSN	00904341
Journal	Archives of Environmental Contamination and Toxicology
Volume Number	65
Issue Number	2
e-ISSN	14320703
Language	English
Publisher	Springer US
Publisher Date	2013-04-06
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Ecotoxicology Pollution Environmental Health Environmental Chemistry Soil Science & Conservation Environmental Monitoring/Analysis
Content Type	Text
Resource Type	Article
Subject	Pollution Health, Toxicology and Mutagenesis Medicine Toxicology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Cadmium Chloride-Induced Disruption of Testicular Steroidogenesis in Rainbow Trout, Oncorhynchus mykiss

Copper Alters the Effect of Temperature on Mitochondrial Bioenergetics in Rainbow Trout, Oncorhynchus mykiss

Fast Genomic Biomarker Responses of Retene and Pyrene in Liver of Juvenile Rainbow Trout, Oncorhynchus mykiss

An Ecological Risk Assessment of the Acute and Chronic Effects of the Herbicide Clopyralid to Rainbow Trout (Oncorhynchus mykiss)

Methoxychlor and Estradiol-17β Affect Alevin Rainbow Trout (Oncorhynchus mykiss) Mortality, Growth, and Pigmentation

An Ecological Risk Assessment of the Exposure and Effects of 2,4-D Acid to Rainbow Trout (Onchorhyncus mykiss)

Biosynthetic Capacity of Rainbow Trout (Oncorhynchus mykiss) Interrenal Tissue After Cadmium Exposure

In Vitro Examination of Interactions Between Copper and Zinc Uptake via the Gastrointestinal Tract of the Rainbow Trout (Oncorhynchus mykiss)

Dietary Pb Accumulation in Juvenile Freshwater Rainbow Trout (Oncorhynchus mykiss)

Induction and Recovery of Estrogenic Effects After Short-Term 17β-Estradiol Exposure in Juvenile Rainbow Trout (Oncorhynchus mykiss)

Similar Documents

Cadmium Chloride-Induced Disruption of Testicular Steroidogenesis in Rainbow Trout, Oncorhynchus mykiss

Copper Alters the Effect of Temperature on Mitochondrial Bioenergetics in Rainbow Trout, Oncorhynchus mykiss

Fast Genomic Biomarker Responses of Retene and Pyrene in Liver of Juvenile Rainbow Trout, Oncorhynchus mykiss

An Ecological Risk Assessment of the Acute and Chronic Effects of the Herbicide Clopyralid to Rainbow Trout (Oncorhynchus mykiss)

Methoxychlor and Estradiol-17β Affect Alevin Rainbow Trout (Oncorhynchus mykiss) Mortality, Growth, and Pigmentation

An Ecological Risk Assessment of the Exposure and Effects of 2,4-D Acid to Rainbow Trout (Onchorhyncus mykiss)

Biosynthetic Capacity of Rainbow Trout (Oncorhynchus mykiss) Interrenal Tissue After Cadmium Exposure

In Vitro Examination of Interactions Between Copper and Zinc Uptake via the Gastrointestinal Tract of the Rainbow Trout (Oncorhynchus mykiss)

Dietary Pb Accumulation in Juvenile Freshwater Rainbow Trout (Oncorhynchus mykiss)

Induction and Recovery of Estrogenic Effects After Short-Term 17β-Estradiol Exposure in Juvenile Rainbow Trout (Oncorhynchus mykiss)