NDLI: Metals and Nonsteroidal Anti-inflammatory Pharmaceuticals Drugs Present in Water from Madín Reservoir (Mexico) Induce Oxidative Stress in Gill, Blood, and Muscle of Common Carp (Cyprinus carpio)

Content Provider	Springer Nature Link
Author	González González, Edgar David Gómez Oliván, Leobardo Manuel Galar Martínez, Marcela Vieyra Reyes, Patricia Islas Flores, Hariz García Medina, Sandra Jiménez Vargas, Juan Manuel Razo Estrada, Celene Pérez Pastén, Ricardo
Copyright Year	2014
Abstract	Many toxic xenobiotics that enter the aquatic environment exert their effects through redox cycling. Oxidative stress, which incorporates both oxidative damage and antioxidant defenses, is a common effect induced in organisms exposed to xenobiotics in their environment. The results of the present study aimed to determine the oxidative stress induced in the common carp Cyprinus carpio by contaminants [metals and nonsteroidal anti-inflammatory drugs (NSAIDs)] present in Madín Reservoir. Five sampling stations (SSs), considered to have the most problems due to discharges, were selected. Carp were exposed to water from each SS for 96 h, and the following biomarkers were evaluated in gill, blood, and muscle: hydroperoxide content, lipid peroxidation, protein carbonyl content, and the activity of antioxidant enzymes superoxide dismutase and catalase. Results show that contaminants (metals and NSAIDs) present in water from the different SSs induce oxidative stress. Thus, water in this reservoir is contaminated with xenobiotics that are hazardous to C. carpio, a species consumed by the local human population.
Starting Page	281
Ending Page	295
Page Count	15
File Format	PDF
ISSN	00904341
Journal	Archives of Environmental Contamination and Toxicology
Volume Number	67
Issue Number	2
e-ISSN	14320703
Language	English
Publisher	Springer US
Publisher Date	2014-06-11
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Ecotoxicology Pollution Environmental Health Environmental Chemistry Soil Science & Conservation Environmental Monitoring/Analysis
Content Type	Text
Resource Type	Article
Subject	Pollution Health, Toxicology and Mutagenesis Medicine Toxicology

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