NDLI: Acute Toxicity and Environmental Risks of Five Veterinary Pharmaceuticals for Aquatic Macroinvertebrates

Content Provider	Springer Nature Link
Author	Bundschuh, Mirco Hahn, Torsten Ehrlich, Bert Höltge, Sibylla Kreuzig, Robert Schulz, Ralf
Copyright Year	2015
Abstract	Due to the high use of antibiotics and antiparasitics for the treatment of livestock, there is concern about the potential impacts of the release of these compounds into freshwater ecosystems. In this context, the present study quantified the acute toxicity of two antibiotics (sulfadiazine and sulfadimidine), and three antiparasitic agents (flubendazole, fenbendazole, ivermectin) for nine freshwater invertebrate species. These experiments revealed a low degree of toxicity for the sulfonamide antibiotics, with limited implications in the survival of all test species at the highest test concentrations (50 and 100 mg/L). In contrast, all three antiparasitic agents indicated on the basis of their acute toxicity risks for the aquatic environment. Moreover, chronic toxicity data from the literature for antiparasitics, including effects on reproduction in daphnids, support the concern about the integrity of aquatic ecosystems posed by releases of these compounds. Thus, these pharmaceuticals warrant further careful consideration by environmental risk managers.
Starting Page	139
Ending Page	143
Page Count	5
File Format	PDF
ISSN	00074861
Journal	Bulletin of Environmental Contamination and Toxicology
Volume Number	96
Issue Number	2
e-ISSN	14320800
Language	English
Publisher	Springer US
Publisher Date	2015-09-25
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Sulfonamide antibiotics Benzimidazole anthelmintics Ivermectin Antiparasitics Predicted no effect concentration Predicted environmental concentration Pollution Environmental Health Ecotoxicology Soil Science & Conservation Environmental Chemistry Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Pollution Medicine Toxicology

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