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| Content Provider | Springer Nature Link |
|---|---|
| Author | Thind, Tarunpreet Singh Singh, Rajbir Kaur, Rajbir Rampal, Geetanjali Arora, Saroj |
| Copyright Year | 2010 |
| Abstract | This study was aimed at evaluating the free radical scavenging activity of methanol extract and fractions from the bark of Schleichera oleosa (Lour.) Oken by employing various well-established in vitro systems such as 2,2′-diphenyl-1-picrylhydrazyl (DPPH), deoxyribose degradation (non-site specific and site specific), reducing power, chelating power, and plasmid nicking assays. Total Phenol Content of the extracts was determined by the assay based on Folin-Ciocalteu’s method. In all the assays, it was observed that the residue fraction, left after the precipitation, was more effective in scavenging the free radicals than the aqueous extract and precipitates. The higher activity of residue fraction may be attributed to the greater amount of phenolic content present in it (942.4 mg/g GAE) as compared to precipitates and aqueous extract. The extract and fractions were found to possess potent antiradical properties, which may be due to either direct scavenging of free radicals or through metal chelation. |
| Starting Page | 254 |
| Ending Page | 260 |
| Page Count | 7 |
| File Format | |
| ISSN | 10542523 |
| Journal | Medicinal Chemistry Research |
| Volume Number | 20 |
| Issue Number | 2 |
| e-ISSN | 15548120 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2010-02-11 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Schleichera oleosa Deoxyribose Reactive oxygen species Total phenolic content Plasmid nicking Cell Biology Biochemistry Pharmacology/Toxicology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Pharmacology, Toxicology and Pharmaceutics |
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