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| Content Provider | Springer Nature Link |
|---|---|
| Author | Frank, Martin Schloissnig, Siegfried |
| Copyright Year | 2010 |
| Abstract | The field of glycobiology is concerned with the study of the structure, properties, and biological functions of the family of biomolecules called carbohydrates. Bioinformatics for glycobiology is a particularly challenging field, because carbohydrates exhibit a high structural diversity and their chains are often branched. Significant improvements in experimental analytical methods over recent years have led to a tremendous increase in the amount of carbohydrate structure data generated. Consequently, the availability of databases and tools to store, retrieve and analyze these data in an efficient way is of fundamental importance to progress in glycobiology. In this review, the various graphical representations and sequence formats of carbohydrates are introduced, and an overview of newly developed databases, the latest developments in sequence alignment and data mining, and tools to support experimental glycan analysis are presented. Finally, the field of structural glycoinformatics and molecular modeling of carbohydrates, glycoproteins, and protein–carbohydrate interaction are reviewed. |
| Starting Page | 2749 |
| Ending Page | 2772 |
| Page Count | 24 |
| File Format | |
| ISSN | 1420682X |
| Journal | Cellular and Molecular Life Sciences |
| Volume Number | 67 |
| Issue Number | 16 |
| e-ISSN | 14209071 |
| Language | English |
| Publisher | SP Birkhäuser Verlag Basel |
| Publisher Date | 2010-04-04 |
| Publisher Place | Basel |
| Access Restriction | Subscribed |
| Subject Keyword | Glyco-bioinformatics Databases Carbohydrates Glycosylation Glycoproteins Molecular modeling Molecular dynamics simulation Biochemistry Life Sciences Biomedicine general Cell Biology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Molecular Biology Molecular Medicine Pharmacology Cellular and Molecular Neuroscience |
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