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  1. Cellular and Molecular Life Sciences
  2. Cellular and Molecular Life Sciences : Volume 67
  3. Cellular and Molecular Life Sciences : Volume 67, Issue 2, January 2010
  4. Key factors in mTOR regulation
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Cellular and Molecular Life Sciences : Volume 73
Cellular and Molecular Life Sciences : Volume 72
Cellular and Molecular Life Sciences : Volume 71
Cellular and Molecular Life Sciences : Volume 70
Cellular and Molecular Life Sciences : Volume 69
Cellular and Molecular Life Sciences : Volume 68
Cellular and Molecular Life Sciences : Volume 67
Cellular and Molecular Life Sciences : Volume 67, Issue 24, December 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 23, December 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 21, November 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 22, November 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 20, October 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 19, October 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 17, September 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 18, September 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 15, August 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 16, August 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 13, July 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 14, July 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 12, June 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 11, June 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 10, May 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 9, May 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 7, April 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 8, April 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 5, March 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 6, March 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 4, February 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 3, February 2010
Cellular and Molecular Life Sciences : Volume 67, Issue 2, January 2010
Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity
Protein transport across and into cell membranes in bacteria and archaea
Insect chitinase and chitinase-like proteins
An overview of RNAs with regulatory functions in gram-positive bacteria
Key factors in mTOR regulation
Reconciling theories of chaperonin accelerated folding with experimental evidence
Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes
γ-radiation-induced γH2AX formation occurs preferentially in actively transcribing euchromatic loci
Hepatocyte growth factor-mediated attraction of mesenchymal stem cells for apoptotic neuronal and cardiomyocytic cells
MEPE evolution in mammals reveals regions and residues of prime functional importance
The p38/MAPK pathway regulates microtubule polymerization through phosphorylation of MAP4 and Op18 in hypoxic cells
Cellular and Molecular Life Sciences : Volume 67, Issue 1, January 2010
Cellular and Molecular Life Sciences : Volume 66
Cellular and Molecular Life Sciences : Volume 65
Cellular and Molecular Life Sciences : Volume 64
Cellular and Molecular Life Sciences : Volume 63
Cellular and Molecular Life Sciences : Volume 62
Cellular and Molecular Life Sciences : Volume 61
Cellular and Molecular Life Sciences : Volume 60
Cellular and Molecular Life Sciences : Volume 59
Cellular and Molecular Life Sciences : Volume 58
Cellular and Molecular Life Sciences : Volume 57
Cellular and Molecular Life Sciences : Volume 56
Cellular and Molecular Life Sciences : Volume 55
Cellular and Molecular Life Sciences : Volume 54
Cellular and Molecular Life Sciences : Volume 53

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Key factors in mTOR regulation

Content Provider Springer Nature Link
Author Bai, Xiaochun Jiang, Yu
Copyright Year 2009
Abstract Mammalian target of rapamycin (mTOR) is a protein serine/threonine kinase that controls a wide range of growth-related cellular processes. In the past several years, many factors have been identified that are involved in controlling mTOR activity. Those factors in turn are regulated by diverse signaling cascades responsive to changes in intracellular and environmental conditions. The molecular connections between mTOR and its regulators form a complex signaling network that governs cellular metabolism, growth and proliferation. In this review, we discuss some key factors in mTOR regulation and mechanisms by which these factors control mTOR activity.
Starting Page 239
Ending Page 253
Page Count 15
File Format PDF
ISSN 1420682X
Journal Cellular and Molecular Life Sciences
Volume Number 67
Issue Number 2
e-ISSN 14209071
Language English
Publisher SP Birkhäuser Verlag Basel
Publisher Date 2009-10-13
Publisher Place Basel
Access Restriction Subscribed
Subject Keyword mTOR TSC2 Rheb FKBP38 PRAS40 hVps34 Rag GTPases Phosphatidic acid Biochemistry Life Sciences Biomedicine general Cell Biology
Content Type Text
Resource Type Article
Subject Cell Biology Molecular Biology Molecular Medicine Pharmacology Cellular and Molecular Neuroscience
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