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  1. Cellular and Molecular Life Sciences
  2. Cellular and Molecular Life Sciences : Volume 58
  3. Cellular and Molecular Life Sciences : Volume 58, Issue 9, August 2001
  4. Pre-menstrual steroids
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Cellular and Molecular Life Sciences : Volume 73
Cellular and Molecular Life Sciences : Volume 72
Cellular and Molecular Life Sciences : Volume 71
Cellular and Molecular Life Sciences : Volume 70
Cellular and Molecular Life Sciences : Volume 69
Cellular and Molecular Life Sciences : Volume 68
Cellular and Molecular Life Sciences : Volume 67
Cellular and Molecular Life Sciences : Volume 66
Cellular and Molecular Life Sciences : Volume 65
Cellular and Molecular Life Sciences : Volume 64
Cellular and Molecular Life Sciences : Volume 63
Cellular and Molecular Life Sciences : Volume 62
Cellular and Molecular Life Sciences : Volume 61
Cellular and Molecular Life Sciences : Volume 60
Cellular and Molecular Life Sciences : Volume 59
Cellular and Molecular Life Sciences : Volume 58
Cellular and Molecular Life Sciences : Volume 58, Issue 14, December 2001
Cellular and Molecular Life Sciences : Volume 58, Issue 12-13, November 2001
Cellular and Molecular Life Sciences : Volume 58, Issue 11, October 2001
Cellular and Molecular Life Sciences : Volume 58, Issue 10, September 2001
Cellular and Molecular Life Sciences : Volume 58, Issue 9, August 2001
Animal cellulases
Lipopeptaibols, a novel family of membrane active, antimicrobial peptides
Tetraspanins
The prolactin releasing peptides: RF-amide peptides
How do thermophilic proteins deal with heat?
Bromelain: biochemistry, pharmacology and medical use
Reverse transcription of retroviruses and LTR retrotransposons
Pre-menstrual steroids
Hepatitis C viral RNA: challenges and promises
Human Genome and Diseases: Review¶Transcription factor GATA3 and the human HDR syndrome
Human Genome and Diseases: Review¶The TSH receptor and its role in thyroid disease
N-terminal acetylation in a third protein family of vertebrate alcohol dehydrogenase/retinal reductase found through a 'proteomics' approach in enzyme characterization
Production of butyrylcholinesterase by Caco-2 cells: lack of relationship with triglyceride production
Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases
Recombinant expression of perchloric acid-soluble protein reduces cell proliferation
Peroxisomes in the apocrine sweat glands of the human axilla and their putative role in pheromone production
Arginase expression in peritoneal macrophages and increase in circulating polyamine levels in mice infected with Schistosoma mansoni
Cellular and Molecular Life Sciences : Volume 58, Issue 8, July 2001
Cellular and Molecular Life Sciences : Volume 58, Issue 7, June 2001
Cellular and Molecular Life Sciences : Volume 58, Issue 5-6, May 2001
Cellular and Molecular Life Sciences : Volume 58, Issue 4, April 2001
Cellular and Molecular Life Sciences : Volume 58, Issue 3, March 2001
Cellular and Molecular Life Sciences : Volume 58, Issue 2, February 2001
Cellular and Molecular Life Sciences : Volume 58, Issue 1, January 2001
Cellular and Molecular Life Sciences : Volume 57
Cellular and Molecular Life Sciences : Volume 56
Cellular and Molecular Life Sciences : Volume 55
Cellular and Molecular Life Sciences : Volume 54
Cellular and Molecular Life Sciences : Volume 53

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Pre-menstrual steroids

Content Provider Springer Nature Link
Author Smith, S.S.
Copyright Year 2001
Abstract A number of steroid hormones and their metabolites fluctuate in the circulation across the human menstrual cycle. In addition to their classic actions on the hypothalamo-pituitary-gonadal axis, many of these hormones act as 'neuroactive steroids' to alter the function of neurotransmitters, such as GABA, within central nervous system circuits. Clinically, these steroids are important because they have not only acute but also long-term effects, and 'withdrawal' properties. This review discusses the effects of steroids such as 3α-OH-5α-pregnan-20-one (3α,5α-THP or allopregnanolone) which alter GABA function in distinct ways dependent upon the time course of exposure, to either enhance or decrease inhibition in the brain. These effects are discussed in light of recent clinical findings which seek to further character-ize the steroid milieu which underlies pre-menstrual dysphoria.
Starting Page 1263
Ending Page 1275
Page Count 13
File Format PDF
ISSN 1420682X
Journal Cellular and Molecular Life Sciences
Volume Number 58
Issue Number 9
e-ISSN 14209071
Language English
Publisher Birkhäuser Verlag
Publisher Date 2001-08-01
Publisher Place Basel
Access Restriction Subscribed
Content Type Text
Resource Type Article
Subject Cell Biology Molecular Biology Molecular Medicine Pharmacology Cellular and Molecular Neuroscience
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