NDLI: Structural and biological aspects of carotenoid cleavage

Content Provider	Springer Nature Link
Author	Kloer, D. P. Schulz, G. E.
Copyright Year	2006
Abstract	Apo-carotenoid compounds such as retinol (vitamin A) are involved in a variety of cellular processes and are found in all kingdoms of life. Instead of being synthesized from small precursors, they are commonly produced by oxidative cleavage and subsequent modification of larger carotenoid compounds. The cleavage reaction is catalyzed by a family of related enzymes, which convert specific substrate double bonds to the corresponding aldehydes or ketones. The individual family members differ in their substrate preference and the position of the cleaved double bond, giving rise to a remarkable number of products starting from a limited number of carotenoid substrate molecules. The recent determination of the structure of a member of this family has provided insight into the reaction mechanism, showing how substrate specificity is achieved. This review will focus on the biochemistry of carotenoid oxygenases and the structural determinants of the cleavage reaction.
Starting Page	2291
Ending Page	2303
Page Count	13
File Format	PDF
ISSN	1420682X
Journal	Cellular and Molecular Life Sciences
Volume Number	63
Issue Number	19
e-ISSN	14209071
Language	English
Publisher	Birkhäuser-Verlag
Publisher Date	2006-08-11
Publisher Place	Basel
Access Restriction	Subscribed
Subject Keyword	Abscisic acid apo-carotenoid BCO (beta-carotene cleavage oxygenase) carotenoid cleavage dioxygenases monooxygenases non-heme iron proteins retinal RPE65 (retinal pigment epithelium 65 kDa protein) Biomedicine general Life Sciences Biochemistry Cell Biology
Content Type	Text
Resource Type	Article
Subject	Cell Biology Molecular Biology Molecular Medicine Pharmacology Cellular and Molecular Neuroscience

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Structural and mechanistic aspects of carotenoid cleavage dioxygenases (CCDs)

Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase

Involvement of the Retinal Pigment Epithelium in the Development of Retinal Lattice Degeneration

Dependence of Retinal Pigment Epithelium Integrity on the NRF2-Heme Oxygenase-1 Axis.

Epidemiology of Mutations in the 65-kDa Retinal Pigment Epithelium (RPE65) Gene-Mediated Inherited Retinal Dystrophies: A Systematic Literature Review.

Naturally Occurring Eccentric Cleavage Products of Provitamin A β-Carotene Function as Antagonists of Retinoic Acid Receptors

Cleavage of pyrogallol by non-heme iron-containing dioxygenases.

Retinoids in the visual cycle: role of the retinal G protein-coupled receptor.

Promoter analysis of RPE65, the gene encoding a 61-kDa retinal pigment epithelium-specific protein.

Structural and biological aspects of carotenoid cleavage

Similar Documents

Structural and mechanistic aspects of carotenoid cleavage dioxygenases (CCDs)

Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase

Involvement of the Retinal Pigment Epithelium in the Development of Retinal Lattice Degeneration

Dependence of Retinal Pigment Epithelium Integrity on the NRF2-Heme Oxygenase-1 Axis.

Epidemiology of Mutations in the 65-kDa Retinal Pigment Epithelium (RPE65) Gene-Mediated Inherited Retinal Dystrophies: A Systematic Literature Review.

Naturally Occurring Eccentric Cleavage Products of Provitamin A β-Carotene Function as Antagonists of Retinoic Acid Receptors

Cleavage of pyrogallol by non-heme iron-containing dioxygenases.

Retinoids in the visual cycle: role of the retinal G protein-coupled receptor.

Promoter analysis of RPE65, the gene encoding a 61-kDa retinal pigment epithelium-specific protein.

Structural and biological aspects of carotenoid cleavage