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Content Provider | Springer Nature Link |
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Author | Gogvadze, Elena Buzdin, Anton |
Copyright Year | 2009 |
Abstract | Retroelements comprise a considerable fraction of eukaryotic genomes. Since their initial discovery by Barbara McClintock in maize DNA, retroelements have been found in genomes of almost all organisms. First considered as a “junk DNA” or genomic parasites, they were shown to influence genome functioning and to promote genetic innovations. For this reason, they were suggested as an important creative force in the genome evolution and adaptation of an organism to altered environmental conditions. In this review, we summarize the up-to-date knowledge of different ways of retroelement involvement in structural and functional evolution of genes and genomes, as well as the mechanisms generated by cells to control their retrotransposition. |
Starting Page | 3727 |
Ending Page | 3742 |
Page Count | 16 |
File Format | |
ISSN | 1420682X |
Journal | Cellular and Molecular Life Sciences |
Volume Number | 66 |
Issue Number | 23 |
e-ISSN | 14209071 |
Language | English |
Publisher | SP Birkhäuser Verlag Basel |
Publisher Date | 2009-08-02 |
Publisher Place | Basel |
Access Restriction | Subscribed |
Subject Keyword | Retroelements Genome rearrangements Alteration of gene expression Genome evolution Cell defense Biochemistry Life Sciences Biomedicine general Cell Biology |
Content Type | Text |
Resource Type | Article |
Subject | Cell Biology Molecular Biology Molecular Medicine Pharmacology Cellular and Molecular Neuroscience |
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