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Single molecule force spectroscopy in biology using the atomic force microscope.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Zlatanova, Jordanka S. Lindsay, Stuart Leuba, Sanford H. |
| Copyright Year | 2000 |
| Abstract | The importance of forces in biology has been recognized for quite a while but only in the past decade have we acquired instrumentation and methodology to directly measure interactive forces at the level of single biological macromolecules and/or their complexes. This review focuses on force measurements performed with the atomic force microscope. A general introduction to the principle of action is followed by review of the types of interactions being studied, describing the main results and discussing the biological implications. |
| Starting Page | 37 |
| Ending Page | 61 |
| Page Count | 25 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/S0079-6107(00)00014-6 |
| PubMed reference number | 11106806 |
| Journal | Medline |
| Volume Number | 74 |
| Issue Number | 1-2 |
| Alternate Webpage(s) | http://www.cbp.pitt.edu/faculty/leuba/pdfs/ZlatanovaLindsayLeubaProgressBiophysMolBiol2001review.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/S0079-6107%2800%2900014-6 |
| Journal | Progress in biophysics and molecular biology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |