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An unusual cause of cancer mimicry following liver transplantation.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Qumosani, Karim Chandok, Natasha |
| Copyright Year | 2012 |
| Abstract | Sirolimus is an approved anti-rejection agent following liver or kidney transplantation that works through inhibition of the mammalian target of rapamycin (mTOR). As sirolimus functions through a pathway independent of calcineurin inhibition, it may have less potential for nephrotoxicity and carcinogenesis. That being said, there are a myriad of potential adverse effects reported with sirolimus, many of which are severe and unknown or poorly understood. Herein we present a case of sirolimus causing a serious but uncommon adverse event in an adult liver transplant recipient; the adverse event in this instance unfortunately resulted in significant medical testing and morbidity. The adverse event profile of sirolimus is summarized through review of available evidence. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/S1665-2681(19)31498-X |
| Alternate Webpage(s) | http://www.medigraphic.com/pdfs/hepato/ah-2012/ah121s.pdf |
| Alternate Webpage(s) | http://annalsofhepatology.com/revista/numeros/2012/Hp121-19.pdf |
| PubMed reference number | 22166573 |
| Alternate Webpage(s) | https://doi.org/10.1016/S1665-2681%2819%2931498-X |
| Journal | Medline |
| Volume Number | 11 |
| Issue Number | 1 |
| Journal | Annals of hepatology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
