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La Cryptococcose Neuro-meningee Au Cours Du Sida : Etude Preliminaire a L'hopital De Bobo-dioulasso (burkina Faso)
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ki-Zerbo, G. Sawadogo, Appolinaire Millogo, Athanase Aa, Yaméogo Ouedraogo, I. Boniface Tamini, M. M. Durand, Gérard |
| Copyright Year | 1996 |
| Abstract | Aids-related cryptococcus neoformans meningitis : preliminary study at Bobo-Dioulasso National Hospital (Burkina Faso) A re t rospective study of impatients hospitalized from mar c h 1993 to march 1995 found that seven patients with AIDS related Cryptococcus neoformans meningitis were admitted at the Internal Medicine clinic of Bobo-Dioulasso Hospital (Burkina-Faso). Five men and two women had C. neoformans meningitis (India ink stain/culture of cerebrospinal fluid). Six patients were HIV seropositives (ELISA-Genelavia) and two w e re HIV 1 (Western-Blot). Diarrhoea, cough, amebic liver abcess, typhoid fever and tuberculous adenitis preceded the o c c u rence of Cryptococcus neoformans meningitis in six patients. Cryptococcosis was inaugural of AIDS in one case. These cases re p resent 3,25 % of the seropositives admitted during the study period and 20,5 % of those who had CSF examination for C. neoformans. Headache (7,/), mental disorders (6/7) and vomiting (5/7) were the main pr e s e n t i n g symptoms. Nuchal rigidity and Kernig’s sign were found in less than half the cases. CSF was always clear and lymphocytic. No major pleocytosis dans albuminorachy was found in most cases by glucose was frankly low in five cases. India ink smear showed C neoformans in six cases and CSF culture was positive in five cases. Isolates were always sensible to Amphotericin B and sensible to Ketoconazole and 5 flucytosine in three out of five cases. Neurologic complic-ations and associated opportunistic condition account for the high m o rtality and short time fo survival (mean 42,5 days). Six patients died and one was lost to follow-up. This study establishe the emergence of AIDS-related cryptococcal disease in Bobo-Dioulasso. Presentation is consistent with advance i m m u n o d e p ression. India ink smear of CSF should be more systematically performed. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.santetropicale.com/resume/14302.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
