NDLI: The Ontario Uterine Fibroid Embolization Trial. Part 2. Uterine fibroid reduction and symptom relief after uterine artery embolization for fibroids.

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The Ontario Uterine Fibroid Embolization Trial. Part 2. Uterine fibroid reduction and symptom relief after uterine artery embolization for fibroids.

Content Provider	Semantic Scholar
Author	Pron, Gaylene E. Bennett, John Wall, Jane Asch, Murray R. Sniderman, Kenneth W.
Copyright Year	2003
Abstract	OBJECTIVE To evaluate fibroid uterine volume reduction, symptom relief, and patient satisfaction with uterine artery embolization (UAE) for symptomatic fibroids. DESIGN Multicenter, prospective, single-arm clinical treatment trial. SETTING Eight Ontario university and community hospitals. Five hundred thirty-eight patients undergoing bilateral UAE. INTERVENTION(S) Bilateral UAE performed with polyvinyl alcohol particles sized 355-500 microm. MAIN OUTCOME MEASURE(S) Three-month follow-up evaluations including fibroid uterine volume reductions, patient reported symptom improvement (7-point scale), symptom life-impact (10-point scale) reduction, and treatment satisfaction (6-point scale). RESULT(S) Median uterine and dominant fibroid volume reductions were 35% and 42%, respectively. Significant improvements were reported for menorrhagia (83%), dysmenorrhea (77%), and urinary frequency/urgency (86%). Mean menstrual duration was significantly reduced after UAE (7.6 to 5.4 days). Improvements in menorrhagia were unrelated to pre-UAE uterine size or post-UAE uterine volume reduction. Amenorrhea occurring after the procedure was highly age dependent, ranging from 3% (1%-7%) in women under age 40 to 41% (26%-58%) in women age 50 or older. Median fibroid life-impact scores were significantly reduced after UAE (8.0 to 3.0). The majority (91%) expressed satisfaction with UAE treatment. CONCLUSION(S) UAE reduced fibroid uterine volume and provided significant relief of menorrhagia that was unrelated to initial fibroid uterine size or volume reduction. Patient satisfaction with short-term UAE treatment outcomes was high.
File Format	PDF HTM / HTML
DOI	10.1016/S0015-0282(02)04538-7
PubMed reference number	12524074
Journal	Medline
Volume Number	79
Issue Number	1
Alternate Webpage(s)	https://virna.mic.ca/assets/uploads/2015/11/Uterine_Fibroid_Embolization_Ontario_part_2.pdf
Alternate Webpage(s)	https://doi.org/10.1016/S0015-0282%2802%2904538-7
Journal	Fertility and sterility
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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