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Group B streptococcal infections in elderly adults.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Edwards, Morven S. Baker, Carol J. |
| Copyright Year | 2005 |
| Abstract | Elderly adults account for >40% of persons with invasive group B streptococcal (GBS) disease and for >50% of GBS-associated deaths in the United States. The prevalence of colonization among healthy elderly adults (approximately 25%) is similar to that among women of childbearing age. Delineating contributions of comorbid conditions, altered integrity of anatomical barriers, and abnormalities in immune responses caused by immune senescence to pathogenesis require further investigation. Delayed clinical recognition of illness may contribute to poor outcome. Skin and soft-tissue infections and bacteremia with no identified focus are common manifestations of infection in elderly adults and younger nonpregnant adults. Urinary tract infection and pneumonia are presentations more often encountered in elderly persons than in younger adults. The safety and immunogenicity of GBS serotype V-tetanus toxoid conjugate vaccine in healthy elderly persons suggest the potential for vaccination as an approach to prevention of invasive GBS infections in elderly persons. |
| Starting Page | 1 |
| Ending Page | 2 |
| Page Count | 2 |
| File Format | PDF HTM / HTML |
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| PubMed reference number | 16107984v1 |
| Volume Number | 41 |
| Issue Number | 6 |
| Journal | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Bacteremia Cessation of life Congenital Abnormality Illness (finding) Immune response Immunostimulating conjugate (antigen) Paget's Disease, Mammary Streptococcal Infections Streptococcal pneumonia Surgical Wound Infection Toxoids Urinary tract infection Vaccines, Conjugate tetanus toxoid vaccine, inactivated |
| Content Type | Text |
| Resource Type | Article |