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The effect of subthalamic nucleus stimulation on kinaesthesia in Parkinson's disease.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Maschke, Matthias Tuite, Paul J. Pickett, Kristen Wächter, Tobias Konczak, Juergen |
| Copyright Year | 2005 |
| Abstract | BACKGROUND Parkinson's disease is accompanied by deficits in passive motion and limb position sense. OBJECTIVE To investigate whether deep brain stimulation of the subthalamic nucleus (STN-DBS) reverses these proprioceptive deficits. METHODS AND RESULTS A passive movement task was applied to nine patients with Parkinson's disease and bilateral chronic STN-DBS and to seven controls. Thresholds for 75% correct responses were 0.9 degrees for controls, 2.5 degrees for Parkinson's disease patients when stimulation was OFF, and 2.0 degrees when stimulation was ON. CONCLUSIONS STN-DBS improves kinaesthesic deficits in Parkinson's disease, but does not lead to a full recovery of proprioceptive function. |
| Starting Page | 259 |
| Ending Page | 262 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://jnnp.bmj.com/content/jnnp/76/4/569.full.pdf |
| PubMed reference number | 15774447v1 |
| Volume Number | 76 |
| Issue Number | 4 |
| Journal | Journal of neurology, neurosurgery, and psychiatry |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Cell Nucleus Cognition Disorders Deep Brain Stimulation Movement Disorders Parkinson Disease Parkinsonian Disorders Patients Streptonigrin Structure of subthalamic nucleus |
| Content Type | Text |
| Resource Type | Article |
