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Antibacterial Activity of the Leaf and Stem Bark of Irvingia gabonensis ( Bush Mango ) Against Escherichia coli and Staphylococcus aureus
| Content Provider | Semantic Scholar |
|---|---|
| Author | Nworie, Okoro Orji, J. O. Ekuma, Uchechukwu Onyeukwu Agah, M. V. Okoli, C. S. Nweke, Michael Chukwugoziem |
| Copyright Year | 2016 |
| Abstract | Bacterial resistance to antibacterial drugs in the treatment of some bacterial infections has become a menace, therefore causing untold health challenges to patients. The antibacterial activity of hot and cold water and ethanolic extract of the leaf and stem bark of Irvingia gabonensis against Escherichia coli and Staphylococcus aureus was evaluated using agar-well diffusion and agar dilution methods. All the organisms were susceptible to all the extracts with the diameter of zones of inhibition ranging between 8mm-23mm for ethanolic extract, 8mm-14mm for hot water extract and 8mm-20mm for cold water extracts. The Minimum Inhibitory Concentration (MIC) ranged between 6.25mg/ml-50mg/ml. The Minimum Bactericidal Concentration (MBC) ranged between 12.5mg/ml-50mg/ml. Sapinin, flavonoids, tannins, cardiac glycosides, anthraquinones, phylobatanins and alkaloids were the phytochemical constituents detected from the irvingia gabonensis stem bark and leaf extract. This study suggests that leaf and bark extract of Irvingia gabonensis has positive antibacterial properties on the test organisms. Further exploration of these plant materials will possibly unveil its potential use for the treatment of disease caused by the test organisms. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.idosi.org/gjp/10(1)16/3.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
