Loading...
Please wait, while we are loading the content...
Similar Documents
Reduced anterior cingulate cortex activity during response inhibition is associated with ad-lib alcohol consumption
| Content Provider | Semantic Scholar |
|---|---|
| Author | Jones, Albert F. Field, Matt Christiansen, Peter Stancák, Andrej |
| Copyright Year | 2012 |
| Abstract | Reduced P300 amplitude during response inhibition is a risk-factor for the development of alcoholism. We examined P300 fluctuations following a manipulation of response conflict during a Stop Signal task, and investigated associations between the inhibition P300 and subsequent ad-lib alcohol consumption. Sixteen participants performed a Stop Signal task under two different levels of response conflict before assessments of ad-lib drinking. EEG source dipole analysis was performed on inhibition trials and compared across conditions. Seven distinct cortical sources of activation were observed on inhibition trials during the Stop Signal task. Increased levels of response conflict led to larger P300 amplitudes associated with increased activation in the proposed site of the anterior cingulate cortex (ACC), both of which were associated with ad-lib drinking immediately after the task. Results provide the first experimental support for theoretical models which posit that reduced ACC activity and the inhibition P300 are risk-factors for heavy drinking. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.appet.2012.05.076 |
| Volume Number | 59 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/S0195666312003315 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/S0195666312003315?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/j.appet.2012.05.076 |
| Journal | Appetite |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
