NDLI: High temporal resolution delayed analysis of clinical microdialysate streams† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7an01209h

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High temporal resolution delayed analysis of clinical microdialysate streams† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7an01209h

Content Provider	Semantic Scholar
Author	Gowers, Sally A. N. Hamaoui, Karim Cunnea, Paula Anastasova, Salzitsa Curto, V. F. Vadgama, Parul Yang, G.-Z. Papalois, Vassilios E. Drakakis, E. M. Fotopoulou, Christina Weber, Stephen G. Boutelle, Martyn G.
Copyright Year	2018
Abstract	This paper presents the use of tubing to store clinical microdialysis samples for delayed analysis with high temporal resolution, offering an alternative to traditional discrete offline microdialysis sampling. Samples stored in this way were found to be stable for up to 72 days at -80 °C. Examples of how this methodology can be applied to glucose and lactate measurement in a wide range of in vivo monitoring experiments are presented. This paper presents a general model, which allows for an informed choice of tubing parameters for a given storage time and flow rate avoiding high back pressure, which would otherwise cause the microdialysis probe to leak, while maximising temporal resolution.
Starting Page	715
Ending Page	724
Page Count	10
File Format	PDF HTM / HTML
DOI	10.1039/c7an01209h
Alternate Webpage(s)	http://pubs.rsc.org/en/content/articlepdf/2018/an/c7an01209h
Alternate Webpage(s)	http://www.rsc.org/suppdata/c7/an/c7an01209h/c7an01209h1.pdf
Alternate Webpage(s)	https://qmro.qmul.ac.uk/xmlui/bitstream/handle/123456789/32429/Vadgama%20High%20temporal%20resolution%202018%20Accepted.pdf?sequence=2
Alternate Webpage(s)	https://pubs.rsc.org/en/content/articlepdf/2018/an/c7an01209h
Alternate Webpage(s)	https://qmro.qmul.ac.uk/xmlui/bitstream/handle/123456789/32429/Vadgama%20High%20temporal%20resolution%202018%20Accepted.pdf?isAllowed=y&sequence=2
PubMed reference number	29336454
Alternate Webpage(s)	https://doi.org/10.1039/c7an01209h
Journal	Medline
Volume Number	143
Journal	The Analyst
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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