NDLI: Epidémiologie de la résistance aux antituberculeux des souches du complexe Mycobacterium tuberculosis isolées d'adénopathies a Djibouti étude prospective realisée en 1999

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Epidémiologie de la résistance aux antituberculeux des souches du complexe Mycobacterium tuberculosis isolées d'adénopathies a Djibouti étude prospective realisée en 1999

Content Provider	Semantic Scholar
Author	Koeck, J-L. Bernatas, J. J. Gérôme, Patrick Fabre, Michel Houmed, Ali Loita Herve, Vincent Teyssou, Rémy
Copyright Year	2002
Abstract	○ La tuberculose est une cause majeure de mortalite a Djibouti, les formes ganglionnaires representant environ 25 % % des formes cliniques. Au cours d'une enquete prospective realisee de janvier a mars 1999, 196 adenopathies ont ete prelevees chez 153 patients residant a Djibouti. La resistance aux antituberculeux etait determinee par la methode des proportions. Une souche du complexe Mycobacterium tuberculosis etait isolee pour 85 patients (Mycobacterium tuberculosis: 78; Mycobacterium canetti: 3; Mycobacterium africanum: 3; Mycobacterium bovis: 1), parmi lesquels 9 etaient prealablement traites. La seroprevalence VIH des patients tuberculeux etait de 15 %. Les resultats de la resistance initiale etaient les suivants: taux global (un ou plusieurs antituberculeux): 18 (21,2 %); isoniazide (H): 6 (7,1 %); rifampicine (R): 3 (3,5 %); ethambutol (E): 1 (1,2 %); streptomycine (S): 13 (15,3 %); pyrazinamide (Z): 1 (1,2 %); multiresistance: 2 (2,4 %). Concernant la resistance acquise, les resultats etaient les suivants: H: 3 (33 %); R: 2 (22 %); S: 2 (22 %); E: 0; Z: 0; multiresistance: 1 (11 %). Les taux de resistance observes ne differaient pas significativement de ceux obtenus pour les prelevements respiratoires analyses entre 1997 et 2000, ni de ceux decrits dans une etude realisee en 1985.
Starting Page	70
Ending Page	72
Page Count	3
File Format	PDF HTM / HTML
Volume Number	62
Alternate Webpage(s)	http://www.jle.com/fr/MedSanteTrop/2002/62.1/070-072%20Epid%C3%A9miologie%20de%20la%20r%C3%A9sistance%20aux%20antituberculeux%20des%20souches%20du%20complexe%20Mycobacterium%20tuberculosis%20isol%C3%A9es%20.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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