NDLI: A dynamic microarray device for paired bead-based analysis.

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A dynamic microarray device for paired bead-based analysis.

Content Provider	Semantic Scholar
Author	Teshima, Tetsuhiko Ishihara, Hirotaka Ibaraki-shi Iwai, Kosuke Adachi, Aki Takeuchi, Shoji
Copyright Year	2010
Abstract	In this study, we have developed a meander-shaped dynamic microfluidic technology that allows us to pair two different types of microbeads in a trapping site. The dynamic microfluidic technology comprises implemented modifications of a conventional dynamic microarray design such as: (i) the combination of a meander-shaped by-pass channel and a trapping channel with a hydrodynamic trapping site and (ii) line-symmetrical formation of the by-pass and trapping channels. Using these modifications, we have successfully trapped different types of sample in one trapping site, and constructed an array of paired beads of different type such as polystyrene beads or hydrogel beads made of agarose, collagen or alginate. We found that this meander-shaped dynamic microfluidic technology is applicable for the observation of interactions between the paired beads such as molecular diffusion.
Starting Page	238ed11
Ending Page	238ed11
Page Count	1
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.rsc.org/suppdata/lc/c0/c004986g/c004986g.pdf
PubMed reference number	20697655v1
Alternate Webpage(s)	https://doi.org/10.1039/c004986g
DOI	10.1039/c004986g
Journal	Lab on a chip
Volume Number	10
Issue Number	18
Language	English
Access Restriction	Open
Subject Keyword	Bead Dosage Form Hydrodynamics Hydrogel Microfluidics Microspheres Polystyrenes
Content Type	Text
Resource Type	Article

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