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Non-uniform distribution of GABA activated chloride channels in cultured cortical neurons
| Content Provider | Semantic Scholar |
|---|---|
| Author | Frosch, Matthew P. Dichter, Marc A. |
| Copyright Year | 1992 |
| Abstract | Several different neurotransmitter receptors and ion channels exist in non-random distributions in the membrane of nerve and muscle cells, a pattern which appears to have functional implications. The data presented here, based on the distribution of single channels in outside-out patches, directly demonstrate that receptors for gamma-aminobutyric acid (GABA) and their associated chloride channels (GABAA receptors) exist almost exclusively in clusters in the membranes of cultured rat cortical neurons. This non-uniform distribution is present both in innervated and uninnervated neurons. |
| Starting Page | 59 |
| Ending Page | 62 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0304-3940(92)90472-J |
| PubMed reference number | 1383879 |
| Journal | Medline |
| Volume Number | 138 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/030439409290472J |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/030439409290472J?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0304-3940%2892%2990472-J |
| Journal | Neuroscience Letters |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |