NDLI: Cholinergic influences on use-dependent plasticity.

Content Provider	Semantic Scholar
Author	Sawaki, Lumy Boroojerdi, Babak Kaelin-Lang, Alain Burstein, Aaron H. Buetefisch, Cathrin M. Kopylev, Leonid Y. Davis, Brian C. Cohen, Leonardo G.
Copyright Year	2002
Abstract	Motor practice elicits use-dependent plasticity in humans as well as in animals. Given the influence of cholinergic neurotransmission on learning and memory processes, we evaluated the effects of scopolamine (a muscarinic receptor antagonist) on use-dependent plasticity and corticomotor excitability in a double-blind placebo-controlled randomized design study. Use-dependent plasticity was substantially attenuated by scopolamine in the absence of global changes in corticomotor excitability. These results identify a facilitatory role for cholinergic influences in use-dependent plasticity in the human motor system.
Starting Page	611
Ending Page	613
Page Count	3
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://jn.physiology.org/content/jn/87/1/166.full.pdf
PubMed reference number	11784739v1
Volume Number	87
Issue Number	1
Journal	Journal of neurophysiology
Language	English
Access Restriction	Open
Subject Keyword	Muscarinic Acetylcholine Receptor Scopolamine Hydrobromide Synaptic Transmission
Content Type	Text
Resource Type	Article

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