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Synthesis of 3-alkyl spiro[4,5]trienones by copper-catalyzed oxidative ipso-annulation of activated alkynes with unactivated alkanes.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ouyang, Xuan-Hui Song, Ren-Jie Li, Jin-Heng |
| Copyright Year | 2016 |
| Abstract | A Cu-catalyzed oxidative ipso-annulation of activated alkynes with unactivated alkanes for the synthesis of 3-alkyl spiro[4,5]trienones is described. This method allows the formation of two carbon-carbon bonds and one carbon-oxygen bond in a single reaction through a sequence of C-H oxidative coupling, ipso-carbocyclization and dearomatization. |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c5cc08952b |
| PubMed reference number | 26744747 |
| Journal | Medline |
| Volume Number | 52 |
| Issue Number | 12 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c5/cc/c5cc08952b/c5cc08952b1.pdf |
| Alternate Webpage(s) | https://doi.org/10.1039/c5cc08952b |
| Journal | Chemical communications |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |