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In-vitro Antibacterial Activity of Acacia e tbaica Against Staphylococcus Aureus and Escherichia coli
| Content Provider | Semantic Scholar |
|---|---|
| Author | Getachew, Belayneh Getachew, Samrawit Mengiste, Berhan Mekuria, Abebe Basazn |
| Copyright Year | 2015 |
| Abstract | This study was conducted to determine the in-vitro anti-microbial activity of Acacia etbaica, native plant to east African countries, against Staphylococcus aureus and Escherichia coli. To achieve this, methanol extract of leaf of Acacia etbaica was tested for its in-vitro antibacterial activity against Staphylococcus aureus and Escherichia coli using agar disc diffusion method at two different concentrations (500μg/disc and 1000μg/disc). The Minimum Inhibitory Concentration (MIC) of the plant crude extract was also determined using micro-dilution method in 96-well plates. Acacia etbaica showed significant antibacterial activity with mean zone of inhibition of 13.34 ± 1.04 mm and 11.13 ± 1.04 mm in diameter at a concentration of 1000μg of plant extract per disc against S. aureus and E. coli respectively. The MIC of the crude extracts of Acacia etbaica was determined to be 0.039mg/ml and 0.313mg/ml against S. aureus and E. coli respectively. The results suggest that the methanol extract of Acacia etbaica could be a rich source of antibacterial compounds. The results also provide an indication of merit in the Acacia etbaica ethnomedicine use by the local communities. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.idosi.org/ajbas/ajbas7(4)15/7.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
