NDLI: Tauroursodeoxycholic Acid Attenuates Lipid Accumulation and Adipogenesis of Adipose-derived Stem Cells

Content Provider	Semantic Scholar
Author	Cha, Byung-Hyun Kim, Jin-Su Ahn, Jong Chan Park, Hansoo Park, Sang-Kyoo Lee, Soo-Hong
Copyright Year	2013
Abstract	SUMMARY Tauroursodeoxycholic acid (TUDCA)– related research suggests that TUDCA have the ability to decrease ER stress, act as leptinsensitizing agents in obese mice and human. TUDCA treatment was able to inhibit adipogenic differentiation of human adiposederived stem cells (hASCs) in the inductive media via decrease in lipid accumulation, while they did not show a significant effect on osteogenic and chondrogenic differentiation. Furthermore, TUDCA treatment was able to inhibit adipogenic differentiation of hASCs by in vivo tissue regeneration.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.controlledreleasesociety.org/meetings/Documents/2013Abstracts/100300.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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