Loading...
Please wait, while we are loading the content...
Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Aldini, Giancarlo Vistoli, Giulio Stefek, Milan Chondrogianni, Niki Grune, Tilman Sereikaite, Jolanta Sadowska-Bartosz, Izabela Bartosz, Grzegorz |
| Copyright Year | 2013 |
| Abstract | The advanced glycoxidation end products (AGEs) and lipoxidation end products (ALEs) contribute to the development of diabetic complications and of other pathologies. The review discusses the possibilities of counteracting the formation and stimulating the degradation of these species by pharmaceuticals and natural compounds. The review discusses inhibitors of ALE and AGE formation, cross-link breakers, ALE/AGE elimination by enzymes and proteolytic systems, receptors for advanced glycation end products (RAGEs) and blockade of the ligand-RAGE axis. |
| Starting Page | 93 |
| Ending Page | 137 |
| Page Count | 45 |
| File Format | PDF HTM / HTML |
| DOI | 10.3109/10715762.2013.792926 |
| PubMed reference number | 23560617 |
| Journal | Medline |
| Volume Number | 47 |
| Alternate Webpage(s) | https://air.unimi.it/retrieve/handle/2434/229971/501722/frr_2013_molecular_strategies.pdf |
| Alternate Webpage(s) | https://doi.org/10.3109/10715762.2013.792926 |
| Journal | Free radical research |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |