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Adherence to and penetration of human intestinal Caco-2 epithelial cell monolayers by Pseudomonas aeruginosa.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hirakata, Yoichi Izumikawa, K. I. Yamaguchi, T. Igimi, Shizunobu Furuya, N. Maesaki, S. Tomono, K. Yamada, Yoshinao Kohno, Seiya Yamaguchi, Keizo Kamihira, Shimeru |
| Copyright Year | 1998 |
| Abstract | Clinical isolates of Pseudomonas aeruginosa from blood adhered to and penetrated intestinal Caco-2 cell monolayers to a greater degree than did isolates from sputum, with a concomitant drastic decrease in transepithelial electrical resistance. PAO-PR1, an avirulent exotoxin A mutant of PAO1, did not cause a decrease in the resistance. The Caco-2 monolayer system may be useful for the evaluation of certain P. aeruginosa virulence factor activities. |
| File Format | PDF HTM / HTML |
| DOI | 10.1128/iai.66.4.1748-1751.1998 |
| PubMed reference number | 9529107 |
| Journal | Medline |
| Volume Number | 66 |
| Issue Number | 4 |
| Alternate Webpage(s) | http://iai.asm.org/content/66/4/1748.full.pdf |
| Alternate Webpage(s) | https://doi.org/10.1128/iai.66.4.1748-1751.1998 |
| Journal | Infection and immunity |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |