Loading...
Please wait, while we are loading the content...
Similar Documents
In vitro antimicrobial and antioxidant properties of Ganoderma lucidum extracts grown in Turkey.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Celik, Gokcen Yuvali Onbaşli, Dilşad Altinsoy, Berrak Dumlupinar Alli, Hakan |
| Copyright Year | 2014 |
| Abstract | Aim:To determine antimicrobial and antioxidative effects of Ganoderma lucidum. Place and Duration of Study:Erciyes University, Faculty of Pharmacy, Pharmaceutical Biotechnology research laboratory,Kayseri, Turkey, between January to .March, 2013. Methodology:Antimicrobial inhibitory effects were carried out on the extracts using disc diffusion method. Antioxidant activities of the ethanolic and methanolic extracts from G.lucidum were evaluated by using 2,2-diphenyl-1-picrylhydrazyl [DPPH] radical scavenging, metal chelating, total flavonoid and total antioxidant activity assays. In addition, the amounts of phenolic compound, β-carotene, and lycopene components in the extracts were determined. Results: The antimicrobial effects of ethanolic and methanolic extracts of G.lucidum were tested against one species of Gram positive bacteria, two species of Gram-negative bacteria and two yeast.The highest inhibitory activity was determined against C.glabrata RSKK 04019 [25± 1 mm, inhibition zone diameter]. On the other hand, the lowest inhibitory activity was determined against C.albicans ATCC 90028 and B.subtilis RSKK 244 [10 ±1 and 10 ± 0 mm, inhibition zone diameter]. DPPH radical scavenging effect was detected in the methanol extract [IC50 = 3.82 ± 0.04 μg/mL] was higher than the ethanol extracts [IC50 = 7.03 ± 0.07 μg/mL]. Compared to reference antioxidant, the methanol and ethanol extracts of G.lucidum provided a lower IC50 than butylated hydoxyanisole [BHA][IC50 = 0.30 ± 0.01 μg/mL]. Phenolic compounds wre the major antioxidant component found in the mushroom extracts. Conclusion:These results showed that G. lucidum may be used in pharmaceutical applications because of its effective antioxidant properties. |
| Starting Page | 709 |
| Ending Page | 722 |
| Page Count | 14 |
| File Format | PDF HTM / HTML |
| DOI | 10.9734/EJMP/2014/8546 |
| Volume Number | 4 |
| Alternate Webpage(s) | http://www.sdiarticle1.org/prh/EJMP_13/2014/Revised-manuscript_version1_8546.pdf |
| Alternate Webpage(s) | https://doi.org/10.9734/EJMP%2F2014%2F8546 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
