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Evolution of protein sequences and structures.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wood, Tim C. Pearson, W. R. |
| Copyright Year | 1999 |
| Abstract | The relationship between sequence similarity and structural similarity has been examined in 36 protein families with five or more diverse members whose structures are known. The structural similarity within a family (as determined with the DALI structure comparison program) is linearly related to sequence similarity (as determined by a Smith-Waterman search of the protein sequences in the structure database). The correlation between structural similarity and sequence similarity is very high; 18 of the 36 families had linear correlation coefficients r>/=0.878, and only nine had correlation coefficients r |
| File Format | PDF HTM / HTML |
| DOI | 10.1006/jmbi.1999.2972 |
| Alternate Webpage(s) | http://www.people.virginia.edu/~wrp/papers/jmb_wrp99.pdf |
| Alternate Webpage(s) | http://bioinfo.mbb.yale.edu/~mbg/clippings/pearson-jmb-seqstruc.pdf |
| Alternate Webpage(s) | http://www.faculty.virginia.edu/wrpearson/papers/jmb_wrp99.pdf |
| Alternate Webpage(s) | http://people.virginia.edu/~wrp/papers/jmb_wrp99.pdf |
| Alternate Webpage(s) | http://faculty.virginia.edu/wrpearson/papers/jmb_wrp99.pdf |
| PubMed reference number | 10452901 |
| Alternate Webpage(s) | https://doi.org/10.1006/jmbi.1999.2972 |
| Journal | Medline |
| Volume Number | 291 |
| Issue Number | 4 |
| Journal | Journal of molecular biology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
