Schönlein-Henoch purpura during pregnancy with successful outcome for mother and newborn

Content Provider	Semantic Scholar
Author	Rieger, Walter Sator, Paul G. Gschnait, Friedrich Breier, Friedrich
Copyright Year	2002
Abstract	BACKGROUND Schönlein-Henoch purpura is a systemic vasculitis that affects vessels of a small caliber and rarely reported in the literature. CASE PRESENTATION We report on a 35-year-old woman who developed palpable purpura with necrotizing cutaneous lesions on the lower limbs at 27 weeks of gestation. She also complained of epigastric pain and arthralgias. Histologic examination of a skin biopsy showed leukocytoclastic vasculitis with intravascular fibrin thrombi. The direct immunofluorescence analysis evidenced vascular deposits of IgA and C3 in the upper and mid-dermis. These findings were consistent with Schönlein-Henoch purpura. There was no evidence of renal involvement or placental dysfunction. The patient was treated with low-dose oral corticosteroids and a healthy infant was delivered by cesarean section. Examination of the placenta and the navel string disclosed no signs of vasculitis or infarction. CONCLUSION Schönlein-Henoch purpura is rarely reported in pregnancy. Treatment with orally administered corticosteroids may lead to a beneficial outcome for mother and newborn.
Starting Page	1
Ending Page	1
Page Count	1
File Format	PDF HTM / HTML
PubMed reference number	11866865
Volume Number	2
Journal	BMC dermatology
Alternate Webpage(s)	http://download-redirector.springer.com/redirect?contentType=pdf&ddsId=art:10.1186/1471-5945-2-1&originUrl=http://bmcdermatol.biomedcentral.com/article/10.1186/1471-5945-2-1
Alternate Webpage(s)	https://core.ac.uk/download/pdf/3187111.pdf
Language	English
Access Restriction	Open
Subject Keyword	Adrenal Cortex Hormones Arthralgia Biopsy of skin procedure Blood Vessel Cesarean section Diameter (qualifier value) Disseminated Intravascular Coagulation Epigastric pain Fluorescent Antibody Technique Henoch-Schoenlein Purpura Infant, Newborn Limb structure Lower Extremity Necrotizing fasciitis Oral cavity Patients Placenta Thrombosis Trophoblastic Tumor, Placental Site Umbilicus (Anatomy) Vasculitis Vasculitis, Leukocytoclastic, Cutaneous
Content Type	Text
Resource Type	Article